4-Ethynyl-N-ethyl-1,8-naphthalimide
Tocris Bioscience, part of Bio-Techne | Catalog # 5712
Click-reactive fluorescent probe. Used for: cell surface imaging. Application: fluorescence microscopy and flow cytometry
Discontinued Product
5712 has been discontinued.
View all Click-Reactive Fluorescent Dyes products.
Key Product Details
Description
Click-reactive fluorescent probe. Used for: cell surface imaging. Application: fluorescence microscopy and flow cytometry
Product Description
Key information: 4-Ethynyl-N-ethyl-1,8-naphthalimide is a click-activated fluorescent probe, for cell surface imaging.Used for: imaging of cell surface and intracellular fucosylated glycoproteins and glycolipids.
Application: suitable for flow cytometry and fluorescence microscopy.
Properties and Photophysical Data: 4-Ethynyl-N-ethyl-1,8-naphthalimide is supplied with an azide reactive handle for copper-free click chemistry reactions.
Optical Data
| Reactive Group | Alkyne |
| Reactivity | Click |
| Application | Confocal Microscopy, Flow Cytometry |
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Product Specifications
Molecular Weight
249.26
Formula
C16H11NO2
Storage
Store at -20°C
Purity
≥98% (HPLC)
Chemical Name
2-Ethyl-6-ethynyl-1H-benz[de]isoquinoline
CAS Number
912921-26-7
PubChem ID
25073575
InChI Key
AYGXEBXIFZUSPD-UHFFFAOYSA-N
SMILES
CCN(C3=O)C(C2=CC=CC1=C(C#C)C=CC3=C12)=O
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 2.49 | 10 with gentle warming |
Preparing Stock Solutions
for 4-Ethynyl-N-ethyl-1,8-naphthalimide
The following data is based on the product molecular weight 249.26
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 40.12 mL | 200.59 mL | 401.19 mL |
| 0.5 mM | 8.02 mL | 40.12 mL | 80.24 mL |
| 1 mM | 4.01 mL | 20.06 mL | 40.12 mL |
| 5 mM | 0.80 mL | 4.01 mL | 8.02 mL |
Calculators
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Background References
References are publications that support the biological activity of the product.
- Sawa Glycoproteomic probes for fluorescent imaging of fucosylated glycans in vivo. Proc.Natl.Acad.Sci.U.S.A. 2006 PMID: 16895981
- Yuan Chemical labeling of 5-iodo-2'-deoxyuridine with 4-ethynyl-N-ethyl-1,8-naphthalimide using copper-free Sonogashira cross-coupling in aqueous medium. Synth.Commun.
Product Specific Notices for 4-Ethynyl-N-ethyl-1,8-naphthalimide
For research use only
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