Rat B7-2/CD86 (NP_064466) VersaClone cDNA
R&D Systems, part of Bio-Techne | Catalog # RDC1770
Key Product Details
Species
Rat
Accession Number
Formulation, Preparation, and Storage
Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Background: B7-2/CD86
B7-2/CD86 and the related B7-1/CD80 are transmembrane cell surface molecules that play important roles in immune activation and the maintenance of immune tolerance. B7-2 is highly expressed on activated antigen presenting cells and vascular endothelial cells. It binds to CD28 on T cells to enhance T cell activation. It additionally binds CTLA-4 which inhibits the T cell response and supports regulatory T cell function. The relative participation of B7-1 and B7-2 in T cell co-stimulation can alter the Th1/Th2 bias of the immune response. Both B7-1 and B7-2 serve as cellular receptors for B species adenoviruses.
Alternate Names
B72, CD86
Gene Symbol
CD86
UniProt
Additional B7-2/CD86 Products
Product Documents for Rat B7-2/CD86 (NP_064466) VersaClone cDNA
Product Specific Notices for Rat B7-2/CD86 (NP_064466) VersaClone cDNA
For research use only
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