Human Wnt-5a (NP_003383.4) VersaClone cDNA
R&D Systems, part of Bio-Techne | Catalog # RDC3681
Key Product Details
Species
Human
Accession Number
Formulation, Preparation, and Storage
Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Background: Wnt-5a
Wnt-5a is a palmitoylated and secreted glycoprotein that is a key molecule in embryonic development and post-natal tissue homeostasis. Wnt‑5a signals through a variety of receptors and cofactors including Frizzled-2, -3, -4, -5, -7, and -8, ROR2, Ryk, MCAM/CD146, LRP-6, sFRP-1, and Vang-like Protein 2. It is expressed by brainstem astrocytes, mammary epithelial cells, CD34+ primitive progenitor stem cells, chondrocytes, vascular pericytes and smooth muscle cells, and mesenchymal cells. Aberrant Wnt-5a expression and function is associated with the development of cancer, fibrosis, and chronic inflammation.
Long Name
Wingless-type MMTV Integration Site Family, Member 5a
Alternate Names
Wnt5a
Gene Symbol
WNT5A
UniProt
Additional Wnt-5a Products
Product Documents for Human Wnt-5a (NP_003383.4) VersaClone cDNA
Product Specific Notices for Human Wnt-5a (NP_003383.4) VersaClone cDNA
For research use only
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