Human STAT2 (NP_005410.1) VersaClone cDNA
R&D Systems, part of Bio-Techne | Catalog # RDC3294
Key Product Details
Species
Human
Accession Number
Formulation, Preparation, and Storage
Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Background: STAT2
Signal transducer and activator of transcription 2 (STAT2) has an apparent M.W. of 113 kDa in SDS-PAGE gels. Human STAT2 is 851 amino acids (aa) in length and contains one SH2 domain (aa 572-667). Splicing variants produce two isoforms for human STAT2. The short isoform has a 32 aa substitution and a 199 aa deletion corresponding to aa 621 - 652 and aa 653 - 851 in the long isoform, respectively. Human STAT2 shares 73% and 65% aa sequence identity with rat and mouse STAT2, in that order. STAT2 functions as a signal transducer and activator of transcription that mediates signaling by type I IFNs (IFN-α and IFN-β), and it is also required for myogenic differentiation.
Long Name
Signal Transducer and Activator of Transcription 2
Alternate Names
interferon alpha induced transcriptional activator, ISGF-3, MGC59816, P113, signal transducer and activator of transcription 2, signal transducer and activator of transcription 2, 113kD, signal transducer and activator of transcription 2, 113kDa, STAT113
Gene Symbol
STAT2
UniProt
Additional STAT2 Products
Product Documents for Human STAT2 (NP_005410.1) VersaClone cDNA
Product Specific Notices for Human STAT2 (NP_005410.1) VersaClone cDNA
For research use only
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