Human KIR2DS3 (NP_036445) VersaClone cDNA
R&D Systems, part of Bio-Techne | Catalog # RDC1898
Key Product Details
Species
Human
Accession Number
Formulation, Preparation, and Storage
Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Background: KIR2DS3
The KIR family is composed of at least 15 members expressed by natural killer (NK) cells and a subset of T cells in primates only. KIR proteins are named based on the number of extracellular Ig-like domains (KIR2D or KIR3D) and for whether the cytoplasmic domain is long (L), or short (S). Inhibitory KIR proteins possess long cytoplasmic tails with ITIM (inhibitory) domains, and several of these molecules bind HLA Class I molecules or target cells. Activating KIR proteins have short tails; their targets are less well-known. KIR2DL4 (CD158d) is unique in that it shows both inhibitory and activating characteristics.
Long Name
Killer Cell Immunoglobulin-Like Receptor, Two Domains, Short Cytoplasmic Tail, 3
Alternate Names
NKAT7
Entrez Gene IDs
3808 (Human)
Gene Symbol
KIR2DS3
UniProt
Additional KIR2DS3 Products
Product Documents for Human KIR2DS3 (NP_036445) VersaClone cDNA
Product Specific Notices for Human KIR2DS3 (NP_036445) VersaClone cDNA
For research use only
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