Human Connexin 26/GJB2 (NP_003995) VersaClone cDNA

R&D Systems, part of Bio-Techne | Catalog # RDC1027

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RDC1027
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Key Product Details

Species

Human

Accession Number

NP_003995

Formulation, Preparation, and Storage

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Storage

Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

Background: Connexin 26/GJB2

Connexin-26 / GJB2 is a gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexins, through which materials of low molecular weight diffuse from one cell to a neighboring cell. Each connexin is composed of a hexamer of connexin proteins. Connexins are a multi-gene family of highly related proteins. At least a dozen distinct connexin genes have been identified and many are expressed in a tissue-specific manner. Two distinct lineages, class I (beta) and class II (alpha), have been identified in mammals. Connexin-26 belongs to the class 1 (beta) group of connexins. Mutations in Connexin-26 are associated with genetically derived hearing impairments, including autosomal recessive non syndromic deafness.

Alternate Names

CX26, DFNA3, DFNB1, GJB2, HID, KID, NSRD1, PPK

Entrez Gene IDs

2706 (Human); 14619 (Mouse); 394266 (Rat)

Gene Symbol

GJB2

UniProt

NP_003995

Additional Connexin 26/GJB2 Products

Product Documents for Human Connexin 26/GJB2 (NP_003995) VersaClone cDNA

Product Datasheets

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Product Specific Notices for Human Connexin 26/GJB2 (NP_003995) VersaClone cDNA

For research use only

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