Human CD98 (NP_001012680) VersaClone cDNA
R&D Systems, part of Bio-Techne | Catalog # RDC0463
Key Product Details
Species
Human
Accession Number
Formulation, Preparation, and Storage
Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Background: CD98
CD98, also known as 4F2, is a widely expressed disulfide-linked heterodimer in the solute transporter family. It consists of an 85 kDa glycosylated type II transmembrane heavy chain and a 40-50 kDa non-glycosylated light chain with 12 transmembrane segments. The heavy chain (SLC3A2) pairs with one of several light chains (SLC7A5, 6, 7, 8, 10, or 11) and is required for the cell surface expression and amino acid transport function of the light chains. CD98 also mediates integrin signaling, T cell costimulation, B cell proliferation, and viral fusion with cell membranes. Within the extracellular region, human CD98 heavy chain shares 73% and 71% aa sequence identity with mouse and rat CD98 heavy chain, respectively.
Alternate Names
4F2, 4F2hc, CD98, CH98hc, FRP-1, SLC3A2
Gene Symbol
SLC3A2
UniProt
Additional CD98 Products
Product Documents for Human CD98 (NP_001012680) VersaClone cDNA
Product Specific Notices for Human CD98 (NP_001012680) VersaClone cDNA
For research use only
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