TNF RI/TNFRSF1A Antibody [Biotin]

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-57667

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NBP3-57667
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Key Product Details

Species Reactivity

Salmon, Zebrafish

Applications

ELISA

Label

Biotin

Antibody Source

Polyclonal Rabbit

Concentration

1 mg/ml

View all TNF RI/TNFRSF1A Antibodies »

Product Specifications

Immunogen

Recombinant TNF RI/TNFRSF1A

Reactivity Notes

Reactivity by species:

Atlantic Salmon TNF-alpha - Strong
Bovine TNF-alpha - None
Canine TNF-alpha - None
Caprine TNF-alpha - Weak
Cynomolgus Monkey TNF-alpha - None
Dolphin TNF-alpha - None
Equine TNF-alpha - None
Feline TNF-alpha - None
Guinea Pig TNF-alpha - None
Human TNF-alpha - None
Mouse TNF-alpha - None
Ovine TNF-alpha - None
Rabbit TNF-alpha - None
Porcine TNF-alpha - None
Zebrafish TNF-alpha - Strong

Clonality

Polyclonal

Host

Rabbit

Applications for TNF RI/TNFRSF1A Antibody [Biotin]

Application
Recommended Usage

ELISA

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Suggested applications: ELISpot

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS

Preservative

0.09% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C.

Background: TNF RI/TNFRSF1A

The protein encoded by the TNF Receptor I gene is a member of the TNF-receptor superfamily. This protein is one of the major receptors for the tumor necrosis factor-alpha. This receptor can activate NF-kappaB, mediate apoptosis, and function as a regulator of inflammation. Antiapoptotic protein BCL2-associated athanogene 4 (BAG4/SODD) and adaptor proteins TRADD and TRAF2 have been shown to interact with this receptor, and thus play regulatory roles in the signal transduction mediated by the receptor. Germline mutations of the extracellular domains of this receptor were found to be associated with the autosomal dominant periodic fever syndrome. The impaired receptor clearance is thought to be a mechanism of the disease. (provided by RefSeq)

Long Name

Tumor Necrosis Factor Receptor I

Alternate Names

CD120a, TNFRI, TNFRSF1A

Gene Symbol

TNFRSF1A

Additional TNF RI/TNFRSF1A Products

Product Documents for TNF RI/TNFRSF1A Antibody [Biotin]

Product Datasheets

Certificate of Analysis

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Product Specific Notices for TNF RI/TNFRSF1A Antibody [Biotin]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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