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TMC1 Antibody [Janelia Fluor® 525]

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-45230JF525

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

ELISA, Immunohistochemistry, Western Blot

Label

Janelia Fluor 525

Antibody Source

Polyclonal Rabbit IgG

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

transmembrane channel-like 1. (Uniprot# Q8TDI8)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Applications for TMC1 Antibody [Janelia Fluor® 525]

Application
Recommended Usage

ELISA

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: TMC1

The TMC1 gene codes a 760 amino acid long, 87 kDA transmembrane channel-like protein 1 that is critical for the function of cochlear hair cells. The specific role of this gene, however, is unknown. This gene is known to interact with genes PRKAA1, MAP1LC3B, GABARAPL2, and NSMAF. Defects in the TMC1 gene cause deafness autosomal dominant type 36 and type 7. Additionally, it has been linked to nonsyndromic deafness, hearing loss, sensorineural hearing loss, megacolon, and enlarged vestibular aqueducts.

Alternate Names

DFNA36, DFNB11, DFNB7, transmembrane channel-like 1, transmembrane channel-like protein 1, Transmembrane cochlear-expressed protein 1, transmembrane, cochlear expressed, 1

Gene Symbol

TMC1

Additional TMC1 Products

Product Documents for TMC1 Antibody [Janelia Fluor® 525]

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for TMC1 Antibody [Janelia Fluor® 525]



Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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