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Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry

Label

DyLight 550 (Excitation = 562 nm, Emission = 576 nm)

Antibody Source

Monoclonal Mouse IgG2B Clone # 622782

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

E.coli-derived recombinant human TCF7L1
Lys429-Ser581
Accession # Q9HCS4

Specificity

Detects human TCF7L1 in direct ELISAs. In direct ELISAs, 5-10% cross-reactivity with recombinant human (rh) TCF-4 (aa 102-516) and rhTCF-12 is observed. No cross-reactivity with rhTCF7L1 (aa 151-320), rhTCF7L2, rhTCF-1, -2, -3, -4 (aa 241-365), rhLEF-1, or recombinant mouse TCF-1 is observed.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2B

Applications for TCF7L1/TCF3 Antibody (622782) [DyLight 550]

Application
Recommended Usage

Immunohistochemistry

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified from hybridoma culture supernatant

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: TCF7L1/TCF3

TCF/LEF transcription factors, such as TCF7L1, are mediators of the Wnt (see MIM 164820) signaling pathway and areantagonized by the TGF-beta (TGFB1; MIM 190180) signaling pathway (Sagara and Katoh, 2000 (PubMed 11085512)).(suppliedby OMIM)

Long Name

Transcription Factor 7-like 1

Alternate Names

TCF3

Gene Symbol

TCF7L1

Additional TCF7L1/TCF3 Products

Product Documents for TCF7L1/TCF3 Antibody (622782) [DyLight 550]

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for TCF7L1/TCF3 Antibody (622782) [DyLight 550]



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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