T Cell Exhaustion Marker (Flow) Antibody Pack
Novus Biologicals, part of Bio-Techne | Catalog # NBP3-12864
![Flow Cytometry: T Cell Exhaustion Marker (Flow) Antibody Pack [NBP3-12864]](https://resources.bio-techne.com/images/products/T-Cell-Exhaustion-Marker-Flow-Flow-Cytometry-img0003.jpg "Flow Cytometry: T Cell Exhaustion Marker (Flow) Antibody Pack [NBP3-12864]")
![Flow Cytometry: T Cell Exhaustion Marker (Flow) Antibody Pack [NBP3-12864]](https://resources.bio-techne.com/images/products/T-Cell-Exhaustion-Marker-Flow-Flow-Cytometry-img0004.jpg "Flow Cytometry: T Cell Exhaustion Marker (Flow) Antibody Pack [NBP3-12864]")
Key Product Details
Species
Human
Applications
CyTOF-ready, Flow Cytometry
Product Summary for T Cell Exhaustion Marker (Flow) Antibody Pack
The Human T Cell Exhaustion Marker Sample Pack (Flow) contains antibodies to detect expression of inhibitory receptors associated with T cell exhaustion including PD-1, CTLA-4, TIGIT, TIM-3, LAG-3 and VISTA. Immune cells expressing these inhibitory receptors are found during chronic viral infection and within the tumor microenvironment of many solid tumors. Also included are three PE-Conjugated secondary antibodies for fluorescent detection by flow cytometry.All antibodies have been validated for use in flow cytometry applications.
This pack contains 1 vial each of:
MAB10863-SP (25 ug):
MAB3253-SP (25 ug)
MAB7898-SP (25 ug)
MAB2365R-SP (25 ug)
MAB71263-SP (25 ug)
MAB23191-SP (25 ug)
F0110 (25ug)
(100 Tests)
F0102B (100 Tests)
F0105B (100 Tests)
This pack contains 1 vial each of:
MAB10863-SP (25 ug):
MAB3253-SP (25 ug)
MAB7898-SP (25 ug)
MAB2365R-SP (25 ug)
MAB71263-SP (25 ug)
MAB23191-SP (25 ug)
F0110 (25ug)
(100 Tests)
F0102B (100 Tests)
F0105B (100 Tests)
Product Specifications
Specificity
Please see each vial's data sheet for specificity information specific to each product.
Application Notes
See individual datasheets of components for their validated applications
Reactivity Notes
See individual datasheets of components for their validated species
Marker
T cell exhaustion
Scientific Data Images for T Cell Exhaustion Marker (Flow) Antibody Pack
![Flow Cytometry: T Cell Exhaustion Marker (Flow) Antibody Pack [NBP3-12864]](https://resources.bio-techne.com/images/products/T-Cell-Exhaustion-Marker-Flow-Flow-Cytometry-img0005.jpg "Flow Cytometry: T Cell Exhaustion Marker (Flow) Antibody Pack [NBP3-12864]")
Flow Cytometry: T Cell Exhaustion Marker (Flow) Antibody Pack [NBP3-12864]
Flow Cytometry: T Cell Exhaustion Marker (Flow) - Human peripheral blood lymphocytes were stained with Mouse Anti-Human TIGIT Monoclonal Antibody (Catalog # MAB7898) followed by Allophycocyanin-conjugated Anti-Mouse IgG Secondary Antibody (Catalog# F0101B) and Mouse Anti-Human NCAM-1/CD56 PE-conjugated Monoclonal Antibody (Catalog# FAB2408P). Quadrant markers were set based on control antibody staining (Catalog# MAB0041).![Flow Cytometry: T Cell Exhaustion Marker (Flow) Antibody Pack [NBP3-12864]](https://resources.bio-techne.com/images/products/T-Cell-Exhaustion-Marker-Flow-Flow-Cytometry-img0001.jpg "Flow Cytometry: T Cell Exhaustion Marker (Flow) Antibody Pack [NBP3-12864]")
Flow Cytometry: T Cell Exhaustion Marker (Flow) Antibody Pack [NBP3-12864]
Flow Cytometry: T Cell Exhaustion Marker (Flow) - Mouse splenocytes were stained with Rat Anti-Mouse CD161/NK1.1 APC-conjugated Monoclonal Antibody (Catalog#: FAB7614A) and either (A) Rabbit Anti-Mouse KLRG1 Monoclonal Antibody (Catalog# MAB6944or (B) Normal Rabbit IgG Control (Catalog# AB-105-C) followed by Phycoerythrin-conjugated Anti-Rabbit IgG Secondary Antibody (Catalog# F0110) at 10 uL/10^6 cells.![Flow Cytometry: T Cell Exhaustion Marker (Flow) Antibody Pack [NBP3-12864]](https://resources.bio-techne.com/images/products/T-Cell-Exhaustion-Marker-Flow-Flow-Cytometry-img0002.jpg "Flow Cytometry: T Cell Exhaustion Marker (Flow) Antibody Pack [NBP3-12864]")
Flow Cytometry: T Cell Exhaustion Marker (Flow) Antibody Pack [NBP3-12864]
Flow Cytometry: T Cell Exhaustion Marker (Flow) - Human peripheral blood mononuclear cells (PBMCs) either (A) treated with 5 ng/mL PHA for 2 days or (B) untreated, were stained with Rabbit Anti-Human PD-1 Monoclonal Antibody (Catalog # MAB10863) followed by Allophycocyanin-conjugated Anti-Rabbit IgG Secondary Antibody (Catalog# F0111) and Mouse Anti-Human CD3 epsilon PE-conjugated Monoclonal Antibody (Catalog# FAB100P). Quadrant markers were set based on control antibody staining (Catalog# MAB1050).Kit Contents for T Cell Exhaustion Marker (Flow) Antibody Pack
- MAB10863-SP
- MAB23191-SP
- MAB2365R-SP
- MAB3253-SP
- MAB71263-SP
- MAB7898-SP
- F0102B: Mouse F(ab)2 IgG (H+L) PE-conjugated Antibody
- F0110: Rabbit IgG PE-conjugated Antibody
- F0105B: Rat F(ab)2 IgG (H+L) PE-conjugated Antibody
Formulation, Preparation, and Storage
Formulation
See individual datasheets
Concentration
Concentration of individual antibodies may be found on the vial label. If unlisted please contact technical services.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Storage
Storage is content dependent.
Background: T Cell Exhaustion Marker (Flow)
Alternate Names
exhaustion markers, immune cell exhaustion, immune checkpoint markers, inhibitory receptors, T cell exhaustion
Additional T Cell Exhaustion Marker (Flow) Products
Product Documents for T Cell Exhaustion Marker (Flow) Antibody Pack
Product Specific Notices for T Cell Exhaustion Marker (Flow) Antibody Pack
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Antibody Packs are guaranteed for 1 year from date of receipt.
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