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Key Product Details

Species Reactivity

Validated:

Human, Mouse, Zebrafish

Cited:

Human, Mouse, Fish - Danio rerio (Zebrafish)

Predicted:

Rat (100%). Backed by our 100% Guarantee.

Applications

Validated:

Immunoprecipitation, Western Blot

Cited:

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1.0 mg/ml

Product Specifications

Immunogen

The immunogen for this product maps to a region between residue 300 and 350 of human Sterol Regulatory Element Binding Transcription Factor 2 using the numbering given in entry NP_004590.2 (GeneID 6721).

Reactivity Notes

Zebrafish reactivity reported in scientific literature (PMID: 24057001). Use in Mouse reported in scientific literature (PMID:28546220).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for SREBP2 Antibody - BSA Free

Western Blot: SREBP2 Antibody [NBP1-71880]

Western Blot: SREBP2 Antibody [NBP1-71880]

SREBP2-Antibody-Western-Blot-NBP1-71880-img0002.jpg
Immunoprecipitation: SREBP2 Antibody [NBP1-71880]

Immunoprecipitation: SREBP2 Antibody [NBP1-71880]

Immunoprecipitation: SREBP2 Antibody [NBP1-71880] - Samples: Whole cell lysate from HeLa (5, 15 and 50 ug for WB; 1 mg for IP, 20% of IP loaded) and 293T (T; 50 ug) cells. Antibodies: Affinity purified rabbit anti-SREBP2 antibody used for WB at 0.4 ug/ml (A) and 1 ug/ml (B) and used for IP at 6 ug/mg lysate. SREBP2 was also immunoprecipitated by rabbit anti-SREBP2 antibody, which recognizes an upstream epitope. Detection: Chemiluminescence with exposure times of 3 minutes (A) and 30 seconds (B).

Applications for SREBP2 Antibody - BSA Free

Application
Recommended Usage

Immunoprecipitation

2- 10 ug/mg lysate

Western Blot

1:1000-1:5000

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris-Citrate/Phosphate (pH 7.0 - 8.0)

Format

BSA Free

Preservative

0.09% Sodium Azide

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: SREBP2

This gene encodes a ubiquitously expressed transcription factor that controls cholesterol homeostasis by stimulating transcription of sterol-regulated genes. The encoded protein contains a basic helix-loop-helix-leucine zipper (bHLH-Zip) domain.

Long Name

Sterol Regulatory Element Binding Transcription Factor 2

Alternate Names

bHLhd2, SREBF2

Entrez Gene IDs

6721 (Human)

Gene Symbol

SREBF2

UniProt

Additional SREBP2 Products

Product Documents for SREBP2 Antibody - BSA Free

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for SREBP2 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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