Slug Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NB100-80828

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NB100-80828
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Key Product Details

Species Reactivity

Validated:

Human, Mouse

Cited:

Human

Applications

Validated:

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot, ELISA, Immunocytochemistry/ Immunofluorescence

Cited:

Western Blot, Immunocytochemistry/ Immunofluorescence, IF/IHC

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1.0 mg/ml

View all Slug Antibodies »

Product Specifications

Immunogen

A 14 amino acid synthetic peptide near the center of human Slug. The immunogen is located within amino acids 70 - 120 of Slug.

Epitope

Near the center, aa 70-120

Specificity

14 amino acid peptide from near the center of human Slug

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Slug Antibody - BSA Free

Western Blot: Slug AntibodyBSA Free [NB100-80828]

Western Blot: Slug AntibodyBSA Free [NB100-80828]

Western Blot: Slug Antibody - BSA Free [NB100-80828] - Human kidney cell lysate with Slug antibody at in (A) 1 and (B) 2 ug/ml.
Immunohistochemistry-Paraffin: Slug Antibody - BSA Free [NB100-80828]

Immunohistochemistry-Paraffin: Slug Antibody - BSA Free [NB100-80828]

Immunohistochemistry-Paraffin: Slug Antibody - BSA Free [NB100-80828] - Staining of human pancreas after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.

Applications for Slug Antibody - BSA Free

Application
Recommended Usage

Immunohistochemistry

10 ug/ml

Immunohistochemistry-Paraffin

10 ug/ml

Western Blot

1-2 ug/ml
Application Notes
Use in ICC/IF reported in scientific literature (PMID 27524413).

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Slug

The zinc finger transcription factor 'snail' was first identified in Drosophila and, along with 'twist', a basic helix-loop-helix transcription factor, is indispensable for mesoderm formation. Snail is a repressor of mouse E-cadherin transcription, with expression of Snail inversely correlated with expression of E-cadherin. Abnormal expression of SNAIL could underlie the tumorigenic conversion of epithelia associated with loss of E-cadherin expression through screening mouse and human cell lines and by in situ hybridization of primary human tumors undergoing malignant progression.

Alternate Names

SLUGH1, SNAI2, SNAIL2, WS2D

Entrez Gene IDs

6591 (Human); 20583 (Mouse)

Gene Symbol

SNAI2

UniProt

O43623 (Human)

Additional Slug Products

Product Documents for Slug Antibody - BSA Free

Product Datasheets

Certificate of Analysis

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Product Specific Notices for Slug Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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