SLC45A4 Antibody

Western Blot: SLC45A4 Antibody [NBP1-70394] -

SLC45A4 is overexpressed in EOC (a) Comparison of SLC45A4 RNA expression between normal ovarian tissue and OC tissue was analyzed using data from TCGA and GEPIA databases. (b) Expression of SLC45A4 in OC tissue in HPA database. (c) IHC analysis showed that SLC45A4 protein expression in EOC was higher than that in normal fallopian tubes and ovaries. Scale = 250 μm.(d) The mRNA and protein expression levels of SLC45A4 in IOSE80, and EOC cells were assessed using qRT-PCR and WB analysis. ∗P < 0.05; ∗∗P < 0.01; ∗∗∗P < 0.001. Image collected and cropped by CiteAb from the following open publication (https://pubmed.ncbi.nlm.nih.gov/39363015), licensed under a CC-BY license. Not internally tested by Novus Biologicals.

Western Blot: SLC45A4 Antibody [NBP1-70394] -

Knockdown of SLC45A4 inhibits proliferation in TP53 mutant PDA cells in vitro. qRT‐PCR (A) and western blotting (B) showed a higher expression of SLC45A4 in TP53 mutant cell lines compared to TP53 wild‐type cell lines. Wt, wild‐type; Mut, mutation. Knockdown of SLC45A4 was confirmed by qRT‐PCR (C) and western blotting (D). MTS (E), colony formation (F) and EdU incorporation (G) assays were performed with si‐SLC45A4 or control cells in hTERT‐HPNE, HPAF‐II and MIA PaCa‐2 cell lines. Scale bar = 200 μm. The data are presented as the mean +/- SD. *p < 0.05, **p < 0.01 and ***p < 0.001 Image collected and cropped by CiteAb from the following open publication (https://pubmed.ncbi.nlm.nih.gov/34010493), licensed under a CC-BY license. Not internally tested by Novus Biologicals.

Western Blot: SLC45A4 Antibody [NBP1-70394] -

Knockout of SLC45A4 suppresses TP53 mutant PDA cell growth in vivo. (A) Knockout of SLC45A4 was detected by western blotting. (B) Knockout of SLC45A4 in HPAF‐II cell inhibited tumor growth in vivo (n = 5 per group). (C) Tumor weights and (D) growth curves of xenograft tumors after subcutaneous injection with KO‐SLC45A4 HPAF‐II cell or the control cell. (E) Representative images are shown of immunohistochemical staining of SLC45A4 and Ki67 with statistical analysis. Data are presented as the mean +/- SD (n = 5). *p < 0.05, **p < 0.01 and ***p < 0.001 Image collected and cropped by CiteAb from the following open publication (https://pubmed.ncbi.nlm.nih.gov/34010493), licensed under a CC-BY license. Not internally tested by Novus Biologicals.