SIGNR1/CD209b Antibody (ER-TR9)
Novus Biologicals, part of Bio-Techne | Catalog # NBP1-42424
Key Product Details
Species Reactivity
Validated:
Mouse
Cited:
Mouse
Applications
Validated:
Immunohistochemistry, Immunohistochemistry-Frozen, Flow Cytometry, Functional
Cited:
Flow Cytometry
Label
Unconjugated
Antibody Source
Monoclonal Rat IgM Clone # ER-TR9
Concentration
This product is unpurified. The exact concentration of antibody is not quantifiable.
Product Specifications
Immunogen
The antibody reacts with the SIGN-R1 antigen.
Specificity
Does not react with macrophages in other regions of the spleen, such as CD169+ marginal metallophils and F4/80+ red pulp macrophages.
Clonality
Monoclonal
Host
Rat
Isotype
IgM
Description
Novus Biologicals Rat SIGNR1/CD209b Antibody (ER-TR9) (NBP1-42424) is a monoclonal antibody validated for use in IHC and Flow. Anti-SIGNR1/CD209b Antibody: Cited in 1 publication. All Novus Biologicals antibodies are covered by our 100% guarantee.
Applications for SIGNR1/CD209b Antibody (ER-TR9)
Application
Recommended Usage
Flow Cytometry
1:10-1:1000
Immunohistochemistry
1:10-1:500
Immunohistochemistry-Frozen
1:10-1:500
Application Notes
Uptake of FITC-labeled dextran by macrophages can be blocked both in vivo and in vitro by the monoclonal antibody ER-TR9. Therefore, the monoclonal antibody ER-TR9 can be used to study the uptake of polysaccharides by macrophages.
Formulation, Preparation, and Storage
Purification
Unpurified
Formulation
Sterile culture medium
Preservative
0.02% Sodium Azide
Concentration
This product is unpurified. The exact concentration of antibody is not quantifiable.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at 4C. Do not freeze.
Background: SIGNR1/CD209b
Mouse SIGNR1 is a type II transmembrane protein that is a homolog of human DCSIGN (R). It is a C-type lectin expressed by marginal zone macrophages and by medullary and subcapsular macrophages in lymph nodes. SIGN R1 binds and mediates the uptake of dextran via mannose and fucose binding sites.
Long Name
SIGN-related 1
Alternate Names
CD209b
Gene Symbol
Cd209a
Additional SIGNR1/CD209b Products
Product Documents for SIGNR1/CD209b Antibody (ER-TR9)
Product Specific Notices for SIGNR1/CD209b Antibody (ER-TR9)
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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