Ret Antibody (C1) - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-42078

Novus Biologicals, part of Bio-Techne
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NBP3-42078
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Key Product Details

Species Reactivity

Mouse

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2b Kappa Clone # C1

Format

BSA Free

Concentration

1 mg/ml

View all Ret Antibodies »

Product Specifications

Immunogen

Immunized with recombinant Mouse Ret (Uniprot#: P35546; Leu29-Phe273 (Uniprot#: P35546)

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2b Kappa

Scientific Data Images for Ret Antibody (C1) - BSA Free

Ret Antibody (C1)

Immunohistochemistry-Paraffin: Ret Antibody (C1) [NBP3-42078] -

Immunohistochemistry-Paraffin: Ret Antibody (C1) [NBP3-42078] - DAB staining on IHC-P; Sample: Mouse Cardiac Muscle Tissue; Primary Ab: 20ug/ml NBP3-42078; Second Ab: 2ug/mL HRP-Linked Caprine Anti-Mouse IgG Polyclonal Antibody
Ret Antibody (C1)

Western Blot: Ret Antibody (C1) [NBP3-42078] -

Western Blot: Ret Antibody (C1) [NBP3-42078] - Sample: K562 cell lysate Primary Ab: 3ug/ml NBP3-42078; Second Ab: 0.2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody

Applications for Ret Antibody (C1) - BSA Free

Application
Recommended Usage

Immunohistochemistry

5-30ug/mL

Immunohistochemistry-Paraffin

5-30ug/mL

Western Blot

0.5-3ug/mL

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

0.01M PBS, pH7.4, 50% glycerol

Format

BSA Free

Preservative

0.05% Proclin 300

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Ret

Ret, a member of the cadherin superfamily, encodes one of the receptor tyrosine kinases, which are cell-surface molecules that transduce signals for cell growth and differentiation. This gene plays a crucial role in neural crest development, and it can undergo oncogenic activation in vivo and in vitro by cytogenetic rearrangement. Mutations in this gene are associated with the disorders multiple endocrine neoplasia, type IIA, multiple endocrine neoplasia, type IIB, Hirschsprung disease, and medullary thyroid carcinoma. Two transcript variants encoding different isoforms have been found for this gene. Additional transcript variants have been described but their biological validity has not been confirmed.

Long Name

Proto-oncogene Tyrosine-protein Kinase Receptor Ret

Alternate Names

CDHF12MTC1, CDHR16, EC 2.7.10, Hirschsprung disease 1, Hirschsprung disease), MEN2A, MEN2B, multiple endocrine neoplasia and medullary thyroid carcinoma 1, ret proto-oncogene, RET transforming sequence

Gene Symbol

RET

Additional Ret Products

Product Documents for Ret Antibody (C1) - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Ret Antibody (C1) - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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