PTEN Antibody (RM265)

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-77408

Recombinant Monoclonal Antibody.
Novus Biologicals, part of Bio-Techne
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NBP2-77408
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Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # RM265

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all PTEN Antibodies »

Product Specifications

Immunogen

A peptide corresponding to the C-terminus of human PTEN

Reactivity Notes

This antibody may also react to mouse PTEN, as predicted by immunogen homology.

Specificity

This antibody reacts to human PTEN and has dual-specificity to protein phosphatase PTEN.

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for PTEN Antibody (RM265)

Western Blot: PTEN Antibody (RM265) [NBP2-77408]

Western Blot: PTEN Antibody (RM265) [NBP2-77408]

Western Blot: PTEN Antibody (RM265) [NBP2-77408] - Western Blot of HeLa and 293 cells lysates using NBP2-77408.
Immunohistochemistry-Paraffin: PTEN Antibody (RM265) [NBP2-77408]

Immunohistochemistry-Paraffin: PTEN Antibody (RM265) [NBP2-77408]

Immunohistochemistry-Paraffin: PTEN Antibody (RM265) [NBP2-77408] - Immunohistochemical staining of formalin fixed and paraffin embedded human melanoma sections using NBP2-77408 at a 1:2000 dilution.
Immunohistochemistry: PTEN Antibody (RM265) [NBP2-77408]

Immunohistochemistry: PTEN Antibody (RM265) [NBP2-77408]

Immunohistochemistry: PTEN Antibody (RM265) [NBP2-77408] - Immunohistochemical staining of formalin fixed and paraffin embedded Human brain tissue sections using NBP2-77408).
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Applications for PTEN Antibody (RM265)

Application
Recommended Usage

Immunohistochemistry

1:1000 - 1:2000

Immunohistochemistry-Paraffin

1:1000 - 1:2000

Western Blot

1:1000 - 1:2000

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

50% Glycerol/PBS, 1% BSA

Preservative

0.09% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: PTEN

PTEN is a protein tyrosine phosphatase that acts as a tumor suppressor, as a lipid phosphatase that dephosphorylates the D3 position of phosphatidylinositol 3,4,5-trisphosphate and as an antagonist of the PI3k/AKT signaling pathway (1-3). PTEN structural domains includes an N-terminal phosphatase domain, a lipid binding C2 domain and a 50-amino acid C-terminal tail that contains a PD biding sequence (5). Phosporylation of the tail of the protein will suppress its activity and modify its conformation to a

Long Name

Phosphatase and Tensin Homolog Deleted on Chromosome 10

Alternate Names

MMAC1

Gene Symbol

PTEN

Additional PTEN Products

Product Documents for PTEN Antibody (RM265)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for PTEN Antibody (RM265)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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