Proprotein Convertase 9/PCSK9 Antibody (DMC222) - Chimeric

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-48296

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-48296-100ug
NBP3-48296-10ug
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Key Product Details

Species Reactivity

Human

Applications

ELISA, Flow Cytometry

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Human IgG1 Clone # DMC222

Concentration

LYOPH mg/ml

View all Proprotein Convertase 9/PCSK9 Antibodies »

Product Specifications

Immunogen

Proprotein Convertase 9/PCSK9 recombinant protein expressed in mammalian cells (Accession# Q8NBP7). The exact amino acid sequence is proprietary.

Clonality

Monoclonal

Host

Human

Isotype

IgG1

Description

This product is shipped at ambient temperature. Store at -20C to -80C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80C (Avoid repeated freezing and thawing).

Scientific Data Images for Proprotein Convertase 9/PCSK9 Antibody (DMC222) - Chimeric

Proprotein Convertase 9/PCSK9 Antibody (DMC222) - Chimeric

Flow Cytometry: Proprotein Convertase 9/PCSK9 Antibody (DMC222) - Chimeric [NBP3-48296]

Flow cytometry analysis with Anti-Proprotein Convertase 9/Proprotein Convertase 9/PCSK9 (DMC222) on HEK293 cells transfected with human Proprotein Convertase 9/Proprotein Convertase 9/PCSK9 (Blue histogram) or HEK293 transfected with irrelevant protein (Red histogram), and Isotype antibody on HEK293 transfected with irrelevant protein (Orange histogram).

Applications for Proprotein Convertase 9/PCSK9 Antibody (DMC222) - Chimeric

Application
Recommended Usage

ELISA

1:5000-10000

Flow Cytometry

1:100

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified from cell culture supernatant

Reconstitution

Dissolve the lyophilized antibody in sterile and low endotoxin water. The recommend volume of water is lot specific. Please refer to the instructions printed on the product vial or contact technical support.

Formulation

PBS, pH 7.4, 5-8% Trehalose

Preservative

Trehalose

Concentration

LYOPH mg/ml

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C in powder form. Store at -80C once reconstituted.

Background: Proprotein Convertase 9/PCSK9

PCSK9 encodes a proprotein convertase belonging to the proteinase K subfamily of the secretory subtilase family. The encoded protein is synthesized as a soluble zymogen that undergoes autocatalytic intramolecular processing in the endoplasmic reticulum. The protein may function as a proprotein convertase. This protein plays a role in cholesterol homeostasis and may have a role in the differentiation of cortical neurons. Mutations in this gene have been associated with a third form of autosomal dominant familial hypercholesterolemia (HCHOLA3).

Alternate Names

FH3, FHCL3, HCHOLA3, LDLCQ1, NARC-1, NARC1, PC9, PCSK9

Gene Symbol

PCSK9

Additional Proprotein Convertase 9/PCSK9 Products

Product Documents for Proprotein Convertase 9/PCSK9 Antibody (DMC222) - Chimeric

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Proprotein Convertase 9/PCSK9 Antibody (DMC222) - Chimeric

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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