PRL/PTP4A Antibody (334407) [HRP]
Novus Biologicals, part of Bio-Techne | Catalog # FAB32191H
Conjugate
Catalog #
Key Product Details
Species Reactivity
Human
Applications
Immunohistochemistry
Label
HRP
Antibody Source
Monoclonal Mouse IgG2B Clone # 334407
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Product Specifications
Immunogen
E. coli-derived recombinant human PRL-3
Ala2-Met173
Accession # O75365
Ala2-Met173
Accession # O75365
Specificity
Detects human PRL-2 and human PRL-3 with equal affinities in direct ELISAs. In direct ELISAs, this antibody shows 10% cross-reactivity with recombinant human PRL-1.
Clonality
Monoclonal
Host
Mouse
Isotype
IgG2B
Applications for PRL/PTP4A Antibody (334407) [HRP]
Application
Recommended Usage
Immunohistochemistry
Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.
Formulation, Preparation, and Storage
Purification
Protein A or G purified from hybridoma culture supernatant
Formulation
PBS
Preservative
No Preservative
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at 4C in the dark.
Background: PRL/PTP4A
PRL (phosphatase of regenerating liver), also known as PTP4A, dephosphorylates tyrosine residues on proteins. Three PRL variants, PRL-1 (PTP4A1), PRL-2 (PTP4A2), and PRL-3 (PTP4A3) have been identified. Prenylation at the C-terminal end targets PRL family members to membrane compartments in the cell, especially to early endosomes and the plasma membrane. PRL levels may correlate with cell migration rates and tumor invasiveness, and PRL overexpression is known to cause an increase in the metastatic capability of cancer cell lines.
Long Name
Phosphatase of Regenerating Liver
Alternate Names
HH72;PRL1;PRL-1;Protein tyrosine phosphatase type IVA 1;PTP(CAAX1);PTP4A1;PTPCAAX1
Additional PRL/PTP4A Products
Product Documents for PRL/PTP4A Antibody (334407) [HRP]
Product Specific Notices for PRL/PTP4A Antibody (334407) [HRP]
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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