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PRICKLE1 Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-46898

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Human, Mouse

Applications

ELISA, Immunoprecipitation, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

prickle homolog 1(Drosophila). (Uniprot# Q96MT3)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for PRICKLE1 Antibody - BSA Free

PRICKLE1 Antibody - BSA Free

Western Blot: PRICKLE1 Antibody - BSA Free [NBP3-46898] -

Western Blot: PRICKLE1 Antibody - BSA Free [NBP3-46898] - Mouse brain tissue were subjected to SDS PAGE followed by western blot with (PRICKLE1 antibody) at dilution of 1:1000
PRICKLE1 Antibody - BSA Free

Immunoprecipitation: PRICKLE1 Antibody - BSA Free [NBP3-46898] -

Immunoprecipitation: PRICKLE1 Antibody - BSA Free [NBP3-46898] - IP Result of anti-PRICKLE1 (IP:, 3ug; Detection: 1:1000) with mouse brain tissue lysate 7000ug.

Applications for PRICKLE1 Antibody - BSA Free

Application
Recommended Usage

Immunoprecipitation

1:200-1:2000

Western Blot

1:500-1:2000
Application Notes
Theoretical Molecular Weight is 94 kDa, 55-60 kDa

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS, 50% Glycerol, pH (7.3)

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: PRICKLE1

PRICKLE1 has 831 amino acids and is approximately 94kDa. PRICKLE1 localizes to the nuclear membrane and is involved in the movement of REST, a transcription repressor. PRICKLE1 is implicated in pathways that regulate neural tube development and gastrulation. PRICKLE1 may also be a nuclear receptor that negatively regulates the Wnt/beta-catenin signaling pathway. Current research on PRICKLE1 is being performed in relation to several diseases and disorders including neural tube defects and progressive myoclonic epilepsy type 1B. PRICKLE1 has also been shown to interact with Dishevelled 1, Dishevelled 2, Dishevelled 3, VIP, and SMURF2 in the Wnt signaling pathway.

Alternate Names

EPM1BMGC138902, FLJ31627, FLJ31937, prickle homolog 1 (Drosophila), prickle-like 1, prickle-like 1 (Drosophila), prickle-like protein 1, REST (RE-1 silencing transcription factor)/NRSF (neuron-restrictive silencerfactor)-interacting LIM domain protein, REST/NRSF-interacting LIM domain protein 1, RILPMGC138903

Gene Symbol

PRICKLE1

Additional PRICKLE1 Products

Product Documents for PRICKLE1 Antibody - BSA Free

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for PRICKLE1 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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