PKC iota/lambda/zeta Antibody [DyLight 755]
Novus Biologicals, part of Bio-Techne | Catalog # AF4465Z
Conjugate
Catalog #
Key Product Details
Species Reactivity
Human, Mouse, Rat
Applications
Immunohistochemistry, Western Blot
Label
DyLight 755 (Excitation = 754 nm, Emission = 776 nm)
Antibody Source
Polyclonal Sheep IgG
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Product Specifications
Immunogen
E. coli-derived recombinant human PKC iota
Ile455-Val596
Accession # P41743
Ile455-Val596
Accession # P41743
Specificity
Detects human, mouse and rat PKC iota/ lambda/ zeta in Western blots.
Clonality
Polyclonal
Host
Sheep
Isotype
IgG
Applications for PKC iota/lambda/zeta Antibody [DyLight 755]
Application
Recommended Usage
Immunohistochemistry
Optimal dilutions of this antibody should be experimentally determined.
Western Blot
Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.
Formulation, Preparation, and Storage
Purification
Antigen Affinity-purified
Formulation
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at 4C in the dark.
Background: PKC iota/lambda/zeta
Atypical members of the Protein Kinase C (PKC) family of serine/threonine protein kinases include PKC iota/lambda and PKC zeta. Members of the atypical PKC subfamily are calcium-independent and do not require phosphatidylserine, diacylglycerol (DAG), or exogenous phorbol esters for activation. They have been shown to serve as convergent downstream targets for the PI 3-kinase and TC10 signaling pathways and can regulate NF-kappa B activation during inflammation and cell survival signaling. Atypical PKCs are also implicated in insulin signaling and glucose regulation.
Long Name
Protein Kinase C iota/lambda/zeta
Additional PKC iota/lambda/zeta Products
Product Documents for PKC iota/lambda/zeta Antibody [DyLight 755]
Product Specific Notices for PKC iota/lambda/zeta Antibody [DyLight 755]
DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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