PKA C (pan) [p Thr197] Antibody (24GB1650)
Novus Biologicals, part of Bio-Techne | Catalog # NBP3-50611
Key Product Details
Species Reactivity
Human, Mouse, Rat
Applications
Western Blot, Flow Cytometry
Label
Unconjugated
Antibody Source
Monoclonal Rabbit IgG Clone # 24GB1650
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Product Specifications
Immunogen
A synthesized peptide derived from human Phospho-PKA C (pan) (Thr197) (Uniprot: P22612/P17612/P22694)
Modification
p Thr197
Specificity
This antibody detects endogenous levels of PRKACG/PRKACA/PRKACB only when phosphorylated at T197
Clonality
Monoclonal
Host
Rabbit
Isotype
IgG
Applications for PKA C (pan) [p Thr197] Antibody (24GB1650)
Application
Recommended Usage
Flow Cytometry
Optimal dilutions of this antibody should be experimentally determined.
Western Blot
Optimal dilutions of this antibody should be experimentally determined.
Formulation, Preparation, and Storage
Purification
Affinity purified
Formulation
PBS (pH 7.4), 50% glycerol
Preservative
0.02% Sodium Azide
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at -20C. Avoid freeze-thaw cycles.
Background: PKA C (pan)
The cAMP-dependent protein kinase (PKA) holoenzyme is composed of two regulatory and two catalytic subunits, designated PKA R and PKA C, respectively. Upon PKA R subunit binding to the second messenger cAMP, active PKA C subunits are released, initiating a phosphorylation cascade that regulates such cellular functions as metabolism, ion transport, and gene transcription. Catalytic PKA subunit isoforms, Cα, Cβ and, in humans, Cγ, have been identified.
Long Name
cAMP-dependent Protein Kinase Catalytic Subunit
Alternate Names
CAFD1, PKACA, PPNAD4
Gene Symbol
PRKACA
Additional PKA C (pan) Products
Product Documents for PKA C (pan) [p Thr197] Antibody (24GB1650)
Product Specific Notices for PKA C (pan) [p Thr197] Antibody (24GB1650)
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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