Nectin-4/PVRL4 Antibody [ADC] - (Enfortumab vedotin-ejfv, Research Grade)

ADC

Monoclonal Human IgG₁

LYOPH mg/ml

Nectin-4/PVRL4 (Uniprot: Q96NY8)

Monoclonal

Human

IgG₁

143.9 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

This product is an Antibody-Drug Conjugate (ADC) for Research Use Only (RUO).

Enfortumab vedotin-ejfv is an ADC consisting of a Nectin-4/PVRL4-directed antibody and Monomethyl auristatin E (MMAE) , suitable for adult patients with locally advanced or metastatic urothelial carcinoma, or who have received programmed cell death protein 1 (PD-1) inhibitor or programmed cell death ligand 1 (PD-L1) inhibitor therapy or neoadjuvant/adjuvant platinum-based chemotherapy for locally advanced or metastatic cancer.

This product is shipped at ambient temperature. Upon receipt, store immediately at -20C or lower for 12 months in a lyophilized state. - 80C for 3 months after reconstitution. Avoid repeated freeze-thaw cycles.

> 90% by SDS-PAGE and HPLC

Reconstitute with sterile, distilled water to a final concentration of 1 mg/ml. Gently shake to solubilize completely. Do not vortex.

Lyophilized from 25mM histidine, 8% sucrose, 0.01% Tween80 (pH6.2)

No Preservative

LYOPH mg/ml

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Store at -20C in powder form. Store at -80C once reconstituted.