NCAM-1/CD56 Antibody [ADC] - (Lorvotuzumab Vedotin, Research Grade)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-44547

Catalog #
Availability
Size / Price
Qty
NBP3-44547
Print Quote
Bulk Order
100% Guarantee

Key Product Details

Species Reactivity

Human

Applications

ELISA, Flow Cytometry, Functional

Label

ADC

Antibody Source

Monoclonal Human IgG1

Concentration

LYOPH mg/ml

View all NCAM-1/CD56 Antibodies »

Product Specifications

Immunogen

NCAM-1/CD56 (Uniprot: P13591)

Clonality

Monoclonal

Host

Human

Isotype

IgG1

Theoretical MW

145 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Description

This product is an Antibody-Drug Conjugate (ADC) for Research Use Only (RUO).

Lorvotuzumab-MMAE is an ADC consisting of an NCAM-directed antibody and Monomethyl auristatin E (MMAE) used for the study of multiple myeloma.

This product is shipped at ambient temperature. Upon receipt, store immediately at -20C or lower for 12 months in a lyophilized state. - 80C for 3 months after reconstitution. Avoid repeated freeze-thaw cycles.

Scientific Data Images for NCAM-1/CD56 Antibody [ADC] - (Lorvotuzumab Vedotin, Research Grade)

Hu NCAM-1/CD56 mAb [ADC] - (Lorvotuzumab Vedotin)

Flow Cytometry: Hu NCAM-1/CD56 mAb [ADC] - (Lorvotuzumab Vedotin)[NBP3-44547]

U251 Cell Line were stained with NCAM-1/CD56 ) and negative control protein respectively, washed and then followed by PE and analyzed with FACS,The EC50 is 0.02 mug/mL.

Applications for NCAM-1/CD56 Antibody [ADC] - (Lorvotuzumab Vedotin, Research Grade)

Application
Recommended Usage

ELISA

Optimal dilutions of this antibody should be experimentally determined.

Flow Cytometry

Optimal dilutions of this antibody should be experimentally determined.

Functional

Optimal dilutions of this antibody should be experimentally determined.

Spectra Viewer

Plan Your Experiments

Use our spectra viewer to interactively plan your experiments, assessing multiplexing options. View the excitation and emission spectra for our fluorescent dye range and other commonly used dyes.

Spectra Viewer

Spectra Viewer

Formulation, Preparation, and Storage

Purification

> 90% by SDS-PAGE and HPLC

Reconstitution

Reconstitute with sterile, distilled water to a final concentration of 1 mg/ml. Gently shake to solubilize completely. Do not vortex.

Formulation

Lyophilized from 25mM histidine, 8% sucrose, 0.01% Tween80 (pH6.2)

Preservative

No Preservative

Concentration

LYOPH mg/ml

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C in powder form. Store at -80C once reconstituted.

Background: NCAM-1/CD56

NCAM, as a member of the immunoglobulin superfamily of adhesion molecules is characterized by several immunoglobulin (Ig) like domains. The extracellular part of NCAM consists of five of these Ig domains and two fibronectin type III homology regions. NCAM is encoded by a single copy gene composed of 26 exons. However, at least 20-30 distinct isoforms can be generated by alternative splicing and by posttranslational modifications, such as sialylation. During sialylation, polysialic acid (PSA) carbohydrates are attached to the extracellular part of NCAM. Through its extracellular region, NCAM mediates homophilic interactions. In addition, NCAM can also undergo heterophilic interactions by binding extracellular matrix components, such as laminin, or other cell adhesion molecules, such as integrins. NCAM is expressed on most neuroectodermal derived cell lines, tissues and neoplasm such as retinoblastoma, medulloblastoma, astrocytomas and neuroblastoma.

Long Name

Neural Cell Adhesion Molecule

Alternate Names

CD56, NCAM1

Additional NCAM-1/CD56 Products

Product Documents for NCAM-1/CD56 Antibody [ADC] - (Lorvotuzumab Vedotin, Research Grade)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Download SDS

Product Specific Notices for NCAM-1/CD56 Antibody [ADC] - (Lorvotuzumab Vedotin, Research Grade)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Privacy Policy
Cookie Policy
Site Map
© Copyright 2026 Bio-Techne. All Rights Reserved. All trademarks and registered trademarks are the property of Bio-Techne and its brands unless otherwise specified.