Mouse PLTP Alexa Fluor™ Plus 647-conjugated Antibody
R&D Systems, part of Bio-Techne | Catalog # AF4918AFP647
Conjugate
Catalog #
Key Product Details
Species Reactivity
Mouse
Applications
Immunohistochemistry, Western Blot
Label
Alexa Fluor Plus 647 (Excitation = 658 nm, Emission = 675 nm)
Antibody Source
Polyclonal Sheep IgG
Product Specifications
Specificity
Detects mouse PLTP in direct ELISAs and Western blots. In direct ELISAs and Western blots, approximately 50% cross-reactivity with recombinant human PLTP is observed.
Clonality
Polyclonal
Host
Sheep
Isotype
IgG
Applications for Mouse PLTP Alexa Fluor™ Plus 647-conjugated Antibody
Application
Recommended Usage
Immunohistochemistry
Optimal dilution of this antibody should be experimentally determined.
Western Blot
Optimal dilution of this antibody should be experimentally determined.
Background: PLTP
PLTP (phospholipid transfer protein) is a 65-80 kDa, secreted glycoprotein member of the BPI/LBP family of proteins. It is expressed by multiple cell types, circulates bound to HDL, and mediates the transfer of phospholipids and cholesterol from apoB-containing lipoproteins to HDL. Mature mouse PLTP is 476 amino acids (aa) in length. It contains an N-terminal lipid transfer domain (aa 21-239), a C-terminal HDL-binding domain (aa 263-463), and one essential intrachain disulfide bond (Cys146‑Cys185). There are three potential PLTP splice variants. One shows a deletion of aa 148-493, a second shows a deletion of aa 111-162, and a third shows a deletion of aa 14-33 plus a two aa substitution for aa 184-493. Over aa 18-493, mouse PLTP shares 92% and 83% aa identity with rat and human PLTP, respectively.
Long Name
Phospholipid Transfer Protein
Alternate Names
HDLCQ9, Lipid transfer protein II, phospholipid transfer protein
Gene Symbol
PLTP
UniProt
Additional PLTP Products
Product Specific Notices for Mouse PLTP Alexa Fluor™ Plus 647-conjugated Antibody
This product is provided under an intellectual property license from Life Technologies Corporation. The transfer of this product is conditioned on the buyer using the purchased product solely in research conducted by the buyer, excluding contract research or any fee for service research, and the buyer must not (1) use this product or its components for (a) diagnostic, therapeutic or prophylactic purposes; (b) testing, analysis or screening services, or information in return for compensation on a per-test basis; or (c) manufacturing or quality assurance or quality control, and/or (2) sell or transfer this product or its components for resale, whether or not resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5781 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@thermofisher.com.
For research use only
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