Detects mouse Integrin alpha3/CD49c in direct ELISAs and Western blots. In direct ELISAs and Western blots, less than 1% cross-reactivity with recombinant mouse (rm) Integrin alpha2, rmIntegrin alpha4, rmIntegrin alpha5, rmIntegrin alphaE, rmIntegrin alphaM, rmIntegrin alphaV and rmIntegrin alphaX is observed.

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Scientific Data Images for Mouse Integrin alpha3/CD49c PE-conjugated Antibody

Detection of Integrin alpha3/CD49c in C2C12 Mouse Cell Line by Flow Cytometry.

C2C12 mouse myoblast cell line was stained with Goat Anti-Mouse Integrin a3/CD49c PE-conjugated Antigen Affinity-purified Polyclonal Antibody (Catalog # FAB2787P, filled histogram) or isotype control antibody (IC108P, open histogram). Staining was performed using our Staining Membrane-associated Proteins protocol.

Detection of Integrin alpha3/CD49c in XB2 Mouse Cell Line by Flow Cytometry.

XB2 mouse teratoma keratinocyte cell line was stained with Goat Anti-Mouse Integrin a3/CD49c PE-conjugated Antigen Affinity-purified Polyclonal Antibody (Catalog # FAB2787P, filled histogram) or isotype control antibody (Catalog # IC108P, open histogram). View our protocol for Staining Membrane-associated Proteins.

Applications for Mouse Integrin alpha3/CD49c PE-conjugated Antibody

Application

Recommended Usage

Flow Cytometry

10 µL/10⁶ cells
Sample: C2C12 mouse myoblast cell line or XB2 mouse teratoma keratinocyte cell line

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

Supplied in a saline solution containing BSA and Sodium Azide.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store the unopened product at 2 - 8° C. Do not use past expiration date. Protect from light.

Background: Integrin alpha 3/CD49c

Integrin alpha3, also known as CD49c and VLA-3 alpha, is a type I membrane protein that heterodimerizes with Integrin beta1. alpha3 beta1 is a cell surface adhesion molecule that functions as a receptor for Laminin, Fibronectin, Collagen, Epiligrin, Thrombospondin and Chondroitin Sulfate Proteoglycan 4. The extracellular domain of human and mouse Integrin alpha3 share approximately 87% amino acid sequence homology.

Alternate Names

CD49c, ITGA3

Entrez Gene IDs

3675 (Human); 16400 (Mouse)

Gene Symbol

ITGA3

UniProt

Q62470

Additional Integrin alpha 3/CD49c Products

Product Documents for Mouse Integrin alpha3/CD49c PE-conjugated Antibody

Product Datasheets

Download Product Datasheets

COA

SDS

Download SDS

Product Specific Notices for Mouse Integrin alpha3/CD49c PE-conjugated Antibody

For research use only

Citations
Reviews

Spectra Viewer
Flow Cytometry

Mouse Integrin alpha3/CD49c PE-conjugated Antibody

R&D Systems, part of Bio-Techne | Catalog # FAB2787P

Key Product Details

Species Reactivity

Validated:

Cited:

Applications