Mouse IL-10 R beta APC-conjugated Antibody
R&D Systems, part of Bio-Techne | Catalog # FAB53681A
Conjugate
Catalog #
Key Product Details
Species Reactivity
Mouse
Applications
Flow Cytometry
Label
Allophycocyanin (Excitation = 620-650 nm, Emission = 660-670 nm)
Antibody Source
Monoclonal Rat IgG2A Clone # 547324
Product Specifications
Immunogen
Mouse myeloma cell line NS0-derived recombinant mouse IL-10 R beta
Ile21-Ser220
Accession # Q61190
Ile21-Ser220
Accession # Q61190
Specificity
Detects mouse IL-10 R beta in direct ELISAs.
Clonality
Monoclonal
Host
Rat
Isotype
IgG2A
Scientific Data Images for Mouse IL-10 R beta APC-conjugated Antibody
Detection of IL‑10 R beta in EL4.IL-2 Mouse Cell Line by Flow Cytometry.
EL4.IL-2 mouse lymphoblast cell line was stained with Rat Anti-Mouse IL-10 R beta APC-conjugated Monoclonal Antibody (Catalog # FAB53681A, filled histogram) or isotype control antibody (Catalog # IC006A, open histogram). View our protocol for Staining Membrane-associated Proteins.Applications for Mouse IL-10 R beta APC-conjugated Antibody
Application
Recommended Usage
Flow Cytometry
0.25-1 µg/106 cells
Sample: EL4.IL-2 mouse lymphoblast cell line
Sample: EL4.IL-2 mouse lymphoblast cell line
Formulation, Preparation, and Storage
Purification
Protein A or G purified from hybridoma culture supernatant
Formulation
Supplied in a saline solution containing BSA and Sodium Azide.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store the unopened product at 2 - 8° C. Do not use past expiration date. Protect from light.
Background: IL-10 R beta
IL-10 R beta (Interleukin 10 receptor beta; also IL-10R2, CD210b and CRF2-4) is an 80-85 kDa member of the type II cytokine receptor family of proteins. It is very widely expressed and serves as a signal transducing accessory chain when complexed to the ligand-binding chains for IL-10, -22, -28A, -28B, and -29 (plus IL-26 in human). Mature mouse IL-10 R beta is a type I transmembrane protein with an extracellular domain that possesses two fibronectin type III domains (aa 22-107 and 111‑208). There is one alternate start site at Met20. Over aa 21- 220, mouse IL-10 R beta shares 87% and 74% aa identity with rat and human IL-10 R beta, respectively.
Long Name
Interleukin 10 Receptor beta
Alternate Names
CDw210b, CRFB4, D21S58, IL-10R2, IL-10Rb, IL10R beta, IL10RB
Gene Symbol
IL10RB
UniProt
Additional IL-10 R beta Products
Product Documents for Mouse IL-10 R beta APC-conjugated Antibody
Product Specific Notices for Mouse IL-10 R beta APC-conjugated Antibody
For research use only
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