Mouse IFN-beta Antibody

Catalog # 22400-1 | R&D Systems, Inc. a Bio-Techne Brand
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Key Product Details

Species Reactivity

Mouse

Applications

Direct ELISA

Label

Unconjugated

Antibody Source

Monoclonal Rat IgG2A Clone # RMMB-1

Product Summary for Mouse IFN-beta Antibody

Immunogen

Human interferon beta

Specificity

Weakly neutralizes mouse interferon beta, but not recommended for neutralization assays; binds to mouse interferon beta

Clonality

Monoclonal

Host

Rat

Isotype

IgG2A

Applications for Mouse IFN-beta Antibody

Application
Recommended Usage

Direct ELISA

Please Note: Optimal dilutions of this antibody should be experimentally determined.

Published Applications

Read 4 publications using 22400-1 in the following applications:

Formulation, Preparation and Storage

Purification

Protein A or G purified from hybridoma culture supernatant

Formulation

Phosphate buffered saline (PBS) containing 0.1% bovine serum albumin (BSA)

Shipping

The product is shipped with dry ice or equivalent. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

After receipt, the product may be stored at -20°C for short-term use (≤ 6 months). For long-term storage, we recommend storing the product at -70°C or below for retention of full activity. When thawing, the contents of the tube should be apportioned in separate tubes so that freezing and thawing is kept to a minimum. Refreezing should be done on dry ice or in a dry ice/alcohol bath. Further dilution of the product should be in buffers containing protein such as 0.1% bovine serum albumin (BSA).

Background: IFN-beta

Interferon-beta (IFN-beta) is a cytokine that is produced by fibroblasts and pathogen-exposed dendritic cells, macrophages, and endothelial cells. It signals through the heterodimeric IFN-alpha/beta Receptor. IFN-beta-deficient mice show increased susceptibility to experimental autoimmune encephalomyelitis (EAE), a disease model of human multiple sclerosis (MS). Furthermore, IFN-beta has been shown to suppress the Th17 cell response in both MS and EAE and has commonly been used as a treatment for MS.

Long Name

Interferon beta

Alternate Names

IFB, IFF, IFNB, IFNB1, IFNbeta

Entrez Gene IDs

3456 (Human); 15977 (Mouse); 24481 (Rat)

Gene Symbol

IFNB1

Product Documents for Mouse IFN-beta Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Note: Certificate of Analysis not available for kit components.

Product Specific Notices for Mouse IFN-beta Antibody

For research use only

Citations for Mouse IFN-beta Antibody (4)

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