MDR1/ABCB1 Antibody (OTI1A7) [PE]

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-72607PE

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Product Datasheet / COA / SDS

View Available Conjugates View Available Formulations

Conjugate

Catalog #

Unconjugated

NBP2-46466

Alexa Fluor 350

NBP2-72607AF350

Alexa Fluor 405

NBP2-72607AF405

Alexa Fluor 488

NBP2-72607AF488

Alexa Fluor 532

NBP2-72607AF532

Alexa Fluor 594

NBP2-72607AF594

Alexa Fluor 647

NBP2-72607AF647

Alexa Fluor 700

NBP2-72607AF700

Alexa Fluor 750

NBP2-72607AF750

Allophycocyanin

NBP2-72607APC

Biotin

NBP2-72607B

CoraFluor 1

NBP2-72607CL1

DyLight 350

NBP2-72607UV

DyLight 405

NBP2-72607V

DyLight 488

NBP2-72607G

DyLight 550

NBP2-72607R

DyLight 594

NBP2-72607DL594

DyLight 650

NBP2-72607C

DyLight 680

NBP2-72607FR

DyLight 755

NBP2-72607IR

FITC

NBP2-72607F

HRP

NBP2-72607H

Janelia Fluor 525

NBP2-72607JF525

Janelia Fluor 549

NBP2-72607JF549

Janelia Fluor 646

NBP2-72607JF646

Janelia Fluor 669

NBP2-72607JF669

mFluor Violet 450 SE

NBP2-72607MFV450

mFluor Violet 500 SE

NBP2-72607MFV500

mFluor Violet 610 SE

NBP2-72607MFV610

PerCP

NBP2-72607PCP

Forumulation

Catalog #

Azide and BSA Free

NBP2-72607

Product Specifications
Applications
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Species Reactivity

Human, Mouse, Rat, Goat

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

PE (Excitation = 488 nm, Emission = 575 nm)

Antibody Source

Monoclonal Mouse IgG_2A Clone # OTI1A7

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all MDR1/ABCB1 Antibodies »

Product Specifications

Immunogen

Human recombinant protein fragment corresponding to amino acids 995-1280 of human ABCB1 (NP_000918) produced in SF9 cell.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG_2A

Applications for MDR1/ABCB1 Antibody (OTI1A7) [PE]

Application

Recommended Usage

Immunohistochemistry

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry-Paraffin

Optimal dilutions of this antibody should be experimentally determined.

Application Notes

Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: MDR1/ABCB1

MDR1 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). MDR1 is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is an ATP-dependent drug efflux pump for xenobiotic compounds with broad substrate specificity. It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs. This protein also functions as a transporter in the blood-brain barrier. (provided by RefSeq)

Long Name

ATP-binding Cassette, Sub-family B (MDR/TAP), Member 1B

Alternate Names

ABC20, ABCB1, ABCB1B, CD243, CLCS, GP170, IBD13, PGY1

Gene Symbol

ABCB1

Additional MDR1/ABCB1 Products

Product Documents for MDR1/ABCB1 Antibody (OTI1A7) [PE]

Product Datasheets

Download Product Datasheets

COA

SDS

Product Specific Notices for MDR1/ABCB1 Antibody (OTI1A7) [PE]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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