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KISS1 Antibody (HL3043)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-48764

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-48764

Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # HL3043

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

Recombinant fragment of human KISS1.

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Description

Novus Biologicals Rabbit KISS1 Antibody (HL3043) (NBP3-48764) is a recombinant monoclonal antibody validated for use in IHC and WB. All Novus Biologicals antibodies are covered by our 100% guarantee.

Scientific Data Images for KISS1 Antibody (HL3043)

KISS1 Antibody (HL3043)

Immunohistochemistry-Paraffin: KISS1 Antibody (HL3043) [NBP3-48764] -

KISS1 antibody [HL3043] detects secreted KISS1 protein by immunohistochemical analysis.Sample: Paraffin-embedded human placenta.KISS1 stained by KISS1 antibody [HL3043] (NBP3-48764) diluted at 1:100.Antigen Retrieval: Citrate buffer, pH 6.0, 15 min

Applications for KISS1 Antibody (HL3043)

Application
Recommended Usage

Western Blot

1:500-1:3000

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Metastin/KiSS1

KISS1 gene encodes metastin, also known as kisspeptin or KiSS-1 peptide, which binds to a G protein-coupled receptor GPR54. KISS1 is dominantly expressed in brain (e.g. anteroventral periventricular nucleus, AVPV arcuate nucleus, ARC), placenta, and pancreas, etc. Metastin plays an important role in regulating the GnRH secretion in brain and MMP-9 expression in placenta, which is associated with development of puberty and sex maturation (e.g. Idiopathic hypogonadotropic hypogonadism, IHH) as well as placentation (e.g. pre-eclampsia), respectively. Metastin was originally discovered as a tumor metastasis suppressor (e.g. melanoma, breast cancer).

Long Name

KiSS-1 Metastasis-suppressor

Alternate Names

KiSS1, Kisspeptin-1

Gene Symbol

KISS1

Additional Metastin/KiSS1 Products

Product Documents for KISS1 Antibody (HL3043)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for KISS1 Antibody (HL3043)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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