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IL-22R alpha 1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NB100-740

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NB100-740-0.025mg

Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, ELISA

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

Synthetic peptide: DSGPEGTPDTVYSIEYKTYGERDWVAKK, corresponding to N terminal amino acids 42-70 of Human IL22 Receptor.

Localization

Cell Membrane

Specificity

IL22 Receptor

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Scientific Data Images for IL-22R alpha 1 Antibody

Immunohistochemistry: IL-22R alpha 1 Antibody [NB100-740]

Immunohistochemistry: IL-22R alpha 1 Antibody [NB100-740]

Immunohistochemistry: IL-22 R alpha 1 Antibody [NB100-740] - Immunohistochemistry with CI0152 on paraffin section of human tonsil.
Immunohistochemistry: IL-22R alpha 1 Antibody [NB100-740]

Immunohistochemistry: IL-22R alpha 1 Antibody [NB100-740]

Immunohistochemistry: IL-22 R alpha 1 Antibody [NB100-740] - Immunohistochemistry with CI0152 on paraffin section of human spleen.

Applications for IL-22R alpha 1 Antibody

Application
Recommended Usage

ELISA

1:100-1:2000

Immunohistochemistry

1:10-1:500

Immunohistochemistry-Paraffin

1:10-1:500
Application Notes
Immunohistochemistry-Paraffin: Perform heat mediated antigen retrieval via the pressure cooker method (with citrate buffer pH 6 or pH 8) before commencing with IHC staining protocol. See recommended protocol. The ELISA dilution is a minimum. Optimal dilutions/concentrations should be determined by the end user. Although not tested this antibody may be useful in Immunocytochemistry/immunoflourescence and Immunohistochemistry-Frozen.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

10mM KHPO4, 0.14M NaCl and 1.0 mg/ml BSA

Preservative

0.1% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: IL-22 R alpha 1

The IL-22RA1 (also termed CRF29 and IL TIFR1 chain) is a new member of the class II cytokine receptor family. IL-22RA1 forms a complex with IL10 Receptor beta chain and mediates IL22 signaling. IL-22RA1 and its receptor activate the JAK/STAT signaling pathway. IL-22RA1 is expressed in normal liver and kidney and their cell lines HepG2 and TK10.

Long Name

Interleukin 22 Receptor

Alternate Names

CRF2-9, IL-22Ra1, IL-TIF-R1, IL22R alpha 1, IL22RA1

Entrez Gene IDs

58985 (Human)

Gene Symbol

IL22RA1

Additional IL-22 R alpha 1 Products

Product Documents for IL-22R alpha 1 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for IL-22R alpha 1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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