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HYPB Antibody (CL9956) - Azide and BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-44227

Novus Biologicals, part of Bio-Techne

Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Human

Applications

Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # CL9956

Format

Azide and BSA Free

Concentration

LYOPH mg/ml

Product Specifications

Immunogen

This antibody was generated using a synthetic peptide of Q9BYW2, with the exact immunogen sequence remaining proprietary.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Scientific Data Images for HYPB Antibody (CL9956) - Azide and BSA Free

HYPB Antibody (CL9956) - Azide and BSA Free Immunohistochemistry-Paraffin: HYPB Antibody [NBP3-44227]

Immunohistochemistry-Paraffin: HYPB Antibody [NBP3-44227]

Analysis in human testis and skeletal muscle tissues using NBP3-44227 antibody. Corresponding HYPB RNA-seq data are presented for the same tissues.
HYPB Antibody (CL9956) - Azide and BSA Free Immunohistochemistry-Paraffin: HYPB Antibody [NBP3-44227]

Immunohistochemistry-Paraffin: HYPB Antibody [NBP3-44227]

Staining of human cervix, uterine shows moderate to strong nuclear positivity in squamous epithelial cells.
HYPB Antibody (CL9956) - Azide and BSA Free Immunohistochemistry-Paraffin: HYPB Antibody [NBP3-44227]

Immunohistochemistry-Paraffin: HYPB Antibody [NBP3-44227]

Staining of human endometrium shows moderate nuclear positivity in glandular cells.

Applications for HYPB Antibody (CL9956) - Azide and BSA Free

Application
Recommended Usage

Immunohistochemistry-Paraffin

1:500 - 1:1000
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Protein A purified

Reconstitution

Centrifuge the vial of lyophilized antibody at 12,000 x g for 20 seconds. Reconstitute by adding sterile, distilled water to achieve a final antibody concentration of 1mg/ml.

Formulation

Lyophilized from a 0.2 um filtered solution in PBS with Trehalose

Format

Azide and BSA Free

Preservative

No Preservative

Concentration

LYOPH mg/ml

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: HYPB

Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein belonging to a class of huntingtin interacting proteins characterized by WW motifs. This protein is a histone methyltransferase that is specific for lysine-36 of histone H3, and methylation of this residue is associated with active chromatin. This protein also contains a novel transcriptional activation domain and has been found associated with hyperphosphorylated RNA polymerase II. (provided by RefSeq)

Alternate Names

FLJ22472, FLJ23184, FLJ45883, FLJ46217, HIF1, HIF-1EC 2.1.1.43, HIP-1, histone-lysine N-methyltransferase SETD2, hSET2, huntingtin interacting protein 1, Huntingtin yeast partner B, Huntingtin-interacting protein 1, Huntingtin-interacting protein B, HYPBp231HBP, KIAA1732SET domain-containing protein 2, KMT3AHBP231, Lysine N-methyltransferase 3A, SET domain containing 2, SET2FLJ16420

Gene Symbol

SETD2

Additional HYPB Products

Product Documents for HYPB Antibody (CL9956) - Azide and BSA Free

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for HYPB Antibody (CL9956) - Azide and BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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