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Key Product Details

Species Reactivity

Mouse

Applications

Western Blot

Label

Janelia Fluor 646

Antibody Source

Polyclonal Goat IgG

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

Mouse myeloma cell line NS0-derived recombinant mouse HVEM/TNFRSF14
Gln39-Val207
Accession # NP_849262

Specificity

Detects mouse HVEM/TNFRSF14 in direct ELISAs and Western blots. In direct ELISAs, approximately 100% cross-reactivity with recombinant rat HVEM/TNFRSF14 is observed, and less than 5% cross-reactivity with recombinant human (rh) HVEM is observed and less than 2% cross-reactivity with recombinant mouse (rm) DR3, rmFas, rmGITR, rmTWEAK R, rm4‑1BB, rmBAFF R, rmCD27, rmCD30, rmCD40, rmEDAR, rmNGF R, rmOX40, rmRANK, rmTNF RI, rmTNF RII, rhDR6, rhTRAIL R3, and rhTRAIL R4 is observed.

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Applications for HVEM/TNFRSF14 Antibody [Janelia Fluor® 646]

Application
Recommended Usage

Western Blot

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: HVEM/TNFRSF14

TNFRSF14 is encoded by this gene is a member of the TNF-receptor superfamily. This receptor was identified as a cellular mediator of herpes simplex virus (HSV) entry. Binding of HSV viral envelope glycoprotein D (gD) to this receptor protein has been shown to be part of the viral entry mechanism. The cytoplasmic region of this receptor was found to bind to several TRAF family members, which may mediate the signal transduction pathways that activate the immune response.

Long Name

Herpesvirus Entry Mediator

Alternate Names

ATAR, CD270, LIGHTR, TNFRSF14

Gene Symbol

TNFRSF14

Additional HVEM/TNFRSF14 Products

Product Documents for HVEM/TNFRSF14 Antibody [Janelia Fluor® 646]

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for HVEM/TNFRSF14 Antibody [Janelia Fluor® 646]



Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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