Solute carrier family 22 member 2 (SLC22A2; also hOCT2) is a 65 kDa member of the major facilitator superfamily and organic cation transporter family of proteins. Human SLC22A2 is synthesized as a multipass transmembrane protein that is 555 amino acids (aa) in length. Human SLC22A2 contains one potential site for N-linked glycosylation. There are also two additional isoforms for human SLC22A2. Isoform 2 has a 57 aa substitution for aa 427-483 and a deletion of the 72 aa at positions 484-555. Isoform 3 has an 18 aa substitution for aa 225-242 and a deletion of residues 243-555. SLC22A2 has its highest expression in the kidney. It is also expressed at lower levels in neurons of the cerebral cortex and in various subcortical nuclei.

Long Name

Organic Cation Transporter 2

Alternate Names

OCT2

Entrez Gene IDs

6582 (Human); 29503 (Rat)

Gene Symbol

SLC22A2

UniProt

O15244

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Product Specific Notices

This product is provided under an intellectual property license from Life Technologies Corporation. The transfer of this product is conditioned on the buyer using the purchased product solely in research conducted by the buyer, excluding contract research or any fee for service research, and the buyer must not (1) use this product or its components for (a) diagnostic, therapeutic or prophylactic purposes; (b) testing, analysis or screening services, or information in return for compensation on a per-test basis; or (c) manufacturing or quality assurance or quality control, and/or (2) sell or transfer this product or its components for resale, whether or not resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5781 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@thermofisher.com.

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Human SLC22A2/OCT2 Alexa Fluor™ Plus 555-conjugated Antibody

R&D Systems, part of Bio-Techne | Catalog # FAB6547AFP555

Key Product Details

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Product Specifications

Immunogen

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Flow Cytometry

Immunohistochemistry

Formulation, Preparation, and Storage

Formulation

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Stability & Storage

Background: SLC22A2/OCT2