Human/Mouse/Rat CCK-AR Antibody
R&D Systems, part of Bio-Techne | Catalog # AF2680
Scientific images may be resized, cropped, or adjusted for brightness or contrast for presentation purposes. These updates are limited to presentation and do not affect the underlying scientific interpretation of the data. Where available, additional source data may be provided upon request.
Discontinued Product
AF2680 has been discontinued.
View all CCK-AR products.
Key Product Details
Species Reactivity
Validated:
Human, Mouse, Rat
Cited:
Rat
Applications
Validated:
Immunohistochemistry, Western Blot
Cited:
Immunohistochemistry-Frozen
Label
Unconjugated
Antibody Source
Polyclonal Rabbit IgG
Product Specifications
Immunogen
Rat CCK-A R synthetic peptide
Lys256-Glu267
Accession # P30551
Lys256-Glu267
Accession # P30551
Specificity
Detects human, mouse, and rat CCK-A R.
Clonality
Polyclonal
Host
Rabbit
Isotype
IgG
Scientific Data Images for Human/Mouse/Rat CCK-AR Antibody
CCK-A R in Rat Pancreas.
CCK-A R was detected in perfusion fixed frozen sections of rat pancreas using 5 µg/mL Human/Mouse/Rat CCK-A R Antigen Affinity-purified Polyclonal Antibody (Catalog # AF2680) overnight at 4 °C. Tissue was stained (red) and counterstained (green). View our protocol for Fluorescent IHC Staining of Frozen Tissue Sections.Applications for Human/Mouse/Rat CCK-AR Antibody
Application
Recommended Usage
Immunohistochemistry
5-15 µg/mL
Sample: Perfusion fixed frozen sections of mouse heart and kidney and rat pancreas
Sample: Perfusion fixed frozen sections of mouse heart and kidney and rat pancreas
Western Blot
0.1 µg/mL
Sample: Recombinant Human CCK-A R
Recombinant Mouse CCK-A R
Recombinant Rat CCK-A R
Sample: Recombinant Human CCK-A R
Recombinant Mouse CCK-A R
Recombinant Rat CCK-A R
Formulation, Preparation, and Storage
Purification
Antigen Affinity-purified
Reconstitution
Reconstitute at 0.2 mg/mL in sterile PBS. For liquid material, refer to CoA for concentration.
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Shipping
Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Background: CCK-AR
The physiologic actions of the cholecystokinin (CCK) family of peptide hormones are mediated through two classes of G protein-coupled receptors, CCK-A R and CCK-B R. CCK-A R is a 428 amino acid protein with 7 putative transmembrane domains. This GPCR is involved in gallbladder contraction, insulin secretion, and has also been described in specific regions of the central nervous system. CCK-A R has been implicated in pancreatic tumorigenesis as well as the pathogenesis of eating disorders and drug addiction.
Long Name
Cholecystokinin Receptor, Type A
Alternate Names
CCK-A R, CCK1R, CCKAR
Gene Symbol
CCKAR
UniProt
Additional CCK-AR Products
Product Documents for Human/Mouse/Rat CCK-AR Antibody
Product Specific Notices for Human/Mouse/Rat CCK-AR Antibody
For research use only
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