Human KIR2DS4/CD158i APC-conjugated Antibody
R&D Systems, part of Bio-Techne | Catalog # FAB1847A
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Conjugate
Catalog #
Key Product Details
Species Reactivity
Validated:
Human
Cited:
Human
Applications
Validated:
Flow Cytometry
Cited:
Flow Cytometry
Label
Allophycocyanin (Excitation = 620-650 nm, Emission = 660-670 nm)
Antibody Source
Monoclonal Mouse IgG2A Clone # 179315
Product Specifications
Immunogen
BaF3 mouse pro-B cell line transfected with human KIR2DS4
Accession # P43632
Accession # P43632
Specificity
Detects KIR2DS4/CD158i in Western blots. In flow cytometry, this antibody stains cells transfected with KIR2DS4/CD158i. Does not stain cells transfected with KIR2DL1, 2DL2, 2DL3, 2DL4, 2DL5, 2DS1, 2DS2, 3DL1, 3DL2, or 3DS1.
Clonality
Monoclonal
Host
Mouse
Isotype
IgG2A
Scientific Data Images for Human KIR2DS4/CD158i APC-conjugated Antibody
Detection of KIR2DS4/CD158i in Human PBMCs by Flow Cytometry.
Human peripheral blood mononuclear cells (PBMCs) were stained with Mouse Anti-Human KIR2DS4/CD158i APC-conjugated Monoclonal Antibody (Catalog # FAB1847A) and Mouse Anti-Human NCAM-1/CD56 PE-conjugated Monoclonal Antibody (Catalog # FAB2408P). Quadrant markers were set based on control antibody staining (Catalog # IC003A). View our protocol for Staining Membrane-associated Proteins.Applications for Human KIR2DS4/CD158i APC-conjugated Antibody
Application
Recommended Usage
Flow Cytometry
10 µL/106 cells
Sample: Human peripheral blood mononuclear cells (PBMCs)
Sample: Human peripheral blood mononuclear cells (PBMCs)
Spectra Viewer
Plan Your Experiments
Use our spectra viewer to interactively plan your experiments, assessing multiplexing options. View the excitation and emission spectra for our fluorescent dye range and other commonly used dyes.
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Formulation, Preparation, and Storage
Purification
Protein A or G purified from hybridoma culture supernatant
Formulation
Supplied in a saline solution containing BSA and Sodium Azide.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Protect from light. Do not freeze.
- 12 months from date of receipt, 2 to 8 °C as supplied.
Background: KIR2DS4/CD158i
KIR2DS4 is an activating immunoglobulin-like receptor expressed on NK cells and some T cells. It has been implicated in the recognition of some HLA-C alleles (1). A deletion variant encoding a single domain secreted isoform of KIR2DS4 has also been described (2).
References
- Katz, G. et al. (2001) J. Immunol. 166:7260.
- Maxwell, L. et al. (2002) Tissue Antigens 60:254.
Long Name
Killer Cell Immunoglobulin-like Receptor, Two Domains, Short Cytoplasmic Tail, 4
Alternate Names
CD158i
Entrez Gene IDs
3809 (Human)
Gene Symbol
KIR2DS4
UniProt
Additional KIR2DS4/CD158i Products
Product Documents for Human KIR2DS4/CD158i APC-conjugated Antibody
Product Specific Notices for Human KIR2DS4/CD158i APC-conjugated Antibody
For research use only
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