Detects human Integrin beta3/CD61 in direct ELISAs and Western blots. In direct ELISAs, no cross-reactivity with recombinant human Integrin beta1, beta2, recombinant mouse Integrin beta4, or beta6 is observed.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG_2A

Scientific Data Images for Human Integrin beta3/CD61 APC-conjugated Antibody

Detection of Integrin beta3/CD61 in Human Peripheral Blood Monocytes by Flow Cytometry.

Human peripheral blood monocytes were stained with Mouse Anti-Human Integrin beta3/CD61 APC-conjugated Monoclonal Antibody (Catalog # FAB2266A, filled histogram) or isotype control antibody (Catalog # IC003A, open histogram). View our protocol for Staining Membrane-associated Proteins.

Applications for Human Integrin beta3/CD61 APC-conjugated Antibody

Application

Recommended Usage

Flow Cytometry

10 µL/10⁶ cells
Sample: Human peripheral blood monocytes

Spectra Viewer

Plan Your Experiments

Use our spectra viewer to interactively plan your experiments, assessing multiplexing options. View the excitation and emission spectra for our fluorescent dye range and other commonly used dyes.

Spectra Viewer

Formulation, Preparation, and Storage

Purification

Protein A or G purified from hybridoma culture supernatant

Formulation

Supplied in a saline solution containing BSA and Sodium Azide.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store the unopened product at 2 - 8° C. Do not use past expiration date. Protect from light.

Background: Integrin beta 3/CD61

Integrin beta3, also called CD61, associates with the Integrin alphaIIb or alphaV subunits to form heterodimeric receptors for collagens, fibronectin, vitronectin, fibrinogen, Von willebrand factor or thrombospondin. alphaIIb/ beta3, also known as GPIIb IIIa (Glycoprotein IIb-IIIa), is expressed on platelets. alphaV/ beta3, also known as vitronectin receptor, is expressed on endothelial cells, some B cells, platelets and monocytes.

Alternate Names

CD61, GP3A, GPIIIA, INGRB3, ITGB3

Entrez Gene IDs

3690 (Human); 16416 (Mouse); 29302 (Rat); 102117791 (Cynomolgus Monkey)

Gene Symbol

ITGB3

UniProt

P05106

Additional Integrin beta 3/CD61 Products

Product Documents for Human Integrin beta3/CD61 APC-conjugated Antibody

Product Datasheets

Download Product Datasheets

COA

SDS

Download SDS

Product Specific Notices for Human Integrin beta3/CD61 APC-conjugated Antibody

For research use only

Citations
Reviews

Human Integrin beta3/CD61 APC-conjugated Antibody

R&D Systems, part of Bio-Techne | Catalog # FAB2266A

Key Product Details

Species Reactivity

Validated:

Cited:

Applications

Validated:

Cited:

Label

Antibody Source

View all Integrin beta 3/CD61 Antibodies »

Product Specifications

Immunogen

Specificity

Clonality

Host

Isotype

Scientific Data Images for Human Integrin beta3/CD61 APC-conjugated Antibody

Detection of Integrin beta3/CD61 in Human Peripheral Blood Monocytes by Flow Cytometry.

Applications for Human Integrin beta3/CD61 APC-conjugated Antibody

Flow Cytometry

Spectra Viewer

Plan Your Experiments

Formulation, Preparation, and Storage

Purification

Formulation

Shipping

Stability & Storage

Background: Integrin beta 3/CD61

Alternate Names

Entrez Gene IDs

Gene Symbol

UniProt

Additional Integrin beta 3/CD61 Products

Product Documents for Human Integrin beta3/CD61 APC-conjugated Antibody

Product Datasheets

COA

Certificate of Analysis

SDS

Product Specific Notices for Human Integrin beta3/CD61 APC-conjugated Antibody