Human IFN-beta Fluorescein MAb (Clone MMHB-3)

R&D Systems, part of Bio-Techne | Catalog # 21400-3

R&D Systems, part of Bio-Techne
Discontinued Product
21400-3 has been discontinued. View all IFN-beta products.

Key Product Details

Species Reactivity

Human

Applications

Flow Cytometry, Immunohistochemistry

Label

Fluorescein (Excitation = 488 nm, Emission = 515-545 nm)

Antibody Source

Monoclonal Mouse IgG1 Clone # MMHB-3

View all IFN-beta Antibodies »

Product Specifications

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Applications for Human IFN-beta Fluorescein MAb (Clone MMHB-3)

Application
Recommended Usage

Flow Cytometry

Immunohistochemistry

Formulation, Preparation, and Storage

Formulation

Phosphate buffered saline (PBS) containing 1% BSA and 0.05% Kathon as a preservative, pH 7.2

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Background: IFN-beta

Interferon-beta (IFN-beta) is a cytokine that is produced by fibroblasts and pathogen-exposed dendritic cells, macrophages, and endothelial cells. It signals through the heterodimeric IFN-alpha/beta Receptor. IFN-beta-deficient mice show increased susceptibility to experimental autoimmune encephalomyelitis (EAE), a disease model of human multiple sclerosis (MS). Furthermore, IFN-beta has been shown to suppress the Th17 cell response in both MS and EAE and has commonly been used as a treatment for MS.

Long Name

Interferon beta

Alternate Names

IFB, IFF, IFNB, IFNB1, IFNbeta

Entrez Gene IDs

3456 (Human); 15977 (Mouse); 24481 (Rat)

Gene Symbol

IFNB1

Additional IFN-beta Products

Product Documents for Human IFN-beta Fluorescein MAb (Clone MMHB-3)

Product Datasheets

Certificate of Analysis

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Note: Certificate of Analysis not available for kit components.

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Product Specific Notices for Human IFN-beta Fluorescein MAb (Clone MMHB-3)

For research use only

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