HPV18 E6 Antibody (C1P5) - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NB100-2729

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Validated:

Virus

Cited:

Human

Applications

Validated:

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot, Immunoprecipitation, Knockdown Validated

Cited:

Western Blot, Immunoprecipitation, IF/IHC, Knockdown Validated

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # C1P5

Format

BSA Free

Concentration

1.0 mg/ml

View all HPV18 E6 Antibodies »

Product Specifications

Immunogen

Gel-purified HPV-18 E6-beta galactosidase fusion protein (amino acids 1-158 of NP_040310.1).

Specificity

Shown to weakly react with HPV16 E6 (PMID 3033140)

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Applications for HPV18 E6 Antibody (C1P5) - BSA Free

Application
Recommended Usage

Immunohistochemistry

1:10-1:500

Immunohistochemistry-Paraffin

1:10-1:500

Immunoprecipitation

1:10-1:500

Knockdown Validated

reported in scientific literature (PMID 31661141)

Western Blot

1:100-1:2000
Application Notes
Reactive on formalin fixed tissue. Reveals a 16.5 kDa MW polypeptide in cells derived from a human cervical carcinoma.

Reviewed Applications

Read 1 review rated 5 using NB100-2729 in the following applications:

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS

Format

BSA Free

Preservative

0.05% Sodium Azide

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: HPV18 E6

This protein is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. Unlike its related family members, this smallest known acidic cytokeratin is not paired with a basic cytokeratin in epithelial cells. It is specifically expressed in the periderm, the transiently superficial layer that envelopes the developing epidermis. Keratin 19 is not expressed in hepatocytes, therefore, antibody to keratin 19 is useful in the identification of liver metastasis. The degree of keratin 19 positivity in breast cancer distinguishes malignant from benign tumours. Keratin 19 is often co-expressed with keratin 7.

Alternate Names

E6, HpV18gp1, Human papillomavirus type 18 E6, Protein E6

Additional HPV18 E6 Products

Product Documents for HPV18 E6 Antibody (C1P5) - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for HPV18 E6 Antibody (C1P5) - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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