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Gelsolin/GSN Antibody (20) - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-05161

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NBP1-05161
NBP1-05161-0.025mg
Conjugate
Catalog #

Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot, ELISA, Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 kappa Clone # 20

Format

BSA Free

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

Gelsolin purified from human plasma

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1 kappa

Description

Concentration for any given batch will be between 0.85 - 1.15 mg/mL.

Scientific Data Images for Gelsolin/GSN Antibody (20) - BSA Free

Western Blot: Gelsolin/GSN Antibody (20)BSA Free [NBP1-05161]

Western Blot: Gelsolin/GSN Antibody (20)BSA Free [NBP1-05161]

Western Blot: Gelsolin/GSN Antibody (20) - BSA Free [NBP1-05161] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 11 Lane 2: RT4 Lane 3: U-251 MG Lane 4: Human Plasma Lane 5: Liver Lane 6: Tonsil
Immunocytochemistry/ Immunofluorescence: Gelsolin/GSN Antibody (20) - BSA Free [NBP1-05161]

Immunocytochemistry/ Immunofluorescence: Gelsolin/GSN Antibody (20) - BSA Free [NBP1-05161]

Immunocytochemistry/Immunofluorescence: Gelsolin/GSN Antibody (20) - BSA Free [NBP1-05161] - Human cell line U-251 MG shows positivity in actin filaments. Antibody dilution: 1:2000
Immunohistochemistry-Paraffin: Gelsolin/GSN Antibody (20) - BSA Free [NBP1-05161]

Immunohistochemistry-Paraffin: Gelsolin/GSN Antibody (20) - BSA Free [NBP1-05161]

Immunohistochemistry-Paraffin: Gelsolin/GSN Antibody (20) - BSA Free [NBP1-05161] - Human Kidney.

Applications for Gelsolin/GSN Antibody (20) - BSA Free

Application
Recommended Usage

ELISA

1:4000

Immunocytochemistry/ Immunofluorescence

1:2000

Immunohistochemistry

1:6000

Immunohistochemistry-Paraffin

1:6000

Western Blot

1:100-1:2000
Application Notes
ELISA: NBP1-05161 does not work as a capture antibody in sandwich ELISA. WB: NBP1-05161 can be used in Western blotting. IHC: NBP1-05161 can be used in Immunohistochemistry. IF: NBP1-05161 can be used in Immunofluorescence.

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

10mM Phosphate (pH 7.4) and 0.5M NaCl

Format

BSA Free

Preservative

0.09% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: Gelsolin/GSN

Gelsolin participates in the extracellular actin scavenger system, binding actin and disaggregating filamentous actin released from dying cells. Actin monomers are then transferred to Gc-globulin. The plasma concentration of gelsolin is reduced in conditions of major actin release, such as acute liver failure, major trauma and rhabdomyolysis, where multi-organ failure is a risk. It has been suggested that gelsolin, like Gc-globulin, can be a prognostic factor in these conditions.

Alternate Names

ADF, AGEL, Brevin, GSN

Gene Symbol

GSN

Additional Gelsolin/GSN Products

Product Documents for Gelsolin/GSN Antibody (20) - BSA Free

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Gelsolin/GSN Antibody (20) - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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