FGF-8 Antibody [FITC]
Novus Biologicals, part of Bio-Techne | Catalog # AF-423-NAF
Conjugate
Catalog #
Key Product Details
Species Reactivity
Mouse
Applications
Immunohistochemistry, Western Blot, Neutralization
Label
FITC (Excitation = 495 nm, Emission = 519 nm)
Antibody Source
Polyclonal Goat IgG
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Product Specifications
Immunogen
E. coli-derived recombinant mouse FGF-8b
Gln23-Arg215
Accession # NP_006110
Gln23-Arg215
Accession # NP_006110
Specificity
Detects mouse FGF‑8b Isoform in direct ELISAs and Western blots. In direct ELISAs and Western blots, less than 1% cross-reactivity with recombinant human (rh) FGF acidic, rhFGF basic, rhFGF-4, rhFGF-5, rhFGF-6, rhFGF-7 and rhFGF-9 is observed. It does, however,cross‑react with recombinant mouse FGF-8c in neutralizing bioassay.
Clonality
Polyclonal
Host
Goat
Isotype
IgG
Applications for FGF-8 Antibody [FITC]
Application
Recommended Usage
Immunohistochemistry
Optimal dilutions of this antibody should be experimentally determined.
Western Blot
Optimal dilutions of this antibody should be experimentally determined.
Neutralization
Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.
Formulation, Preparation, and Storage
Purification
Antigen Affinity-purified
Formulation
PBS
Preservative
0.05% Sodium Azide
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at 4C in the dark.
Background: FGF-8
Fibroblast Growth Factor 8 (FGF-8) is widely expressed during embryogenesis where it plays an organizing and inducing role during gastrulation and regulates patterning of the midbrain/hindbrain, eye, ear, limbs, and heart. Multiple alternative splice isoforms play distinct roles in development as well as epithelial-mesenchymal transition. They also show differential agonist activity towards the various isoforms of FGF R1, R2, R3, R4, and R5. FGF-8 is weakly expressed in yhe adult reproductive and genitourinary tract, peripheral leukocytes, and bone marrow hematopoietic cells.
Long Name
Fibroblast Growth Factor 8
Alternate Names
AIGF, FGF8, HBGF-8
Gene Symbol
FGF8
Additional FGF-8 Products
Product Documents for FGF-8 Antibody [FITC]
Product Specific Notices for FGF-8 Antibody [FITC]
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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