Epstein Barr Virus Nuclear Antigen 3A Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-66589

Novus Biologicals, part of Bio-Techne
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NBP2-66589
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Key Product Details

Species Reactivity

Virus

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Sheep IgG

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all Epstein Barr Virus Nuclear Antigen 3A Antibodies »

Product Specifications

Immunogen

Recombinant EBNA-3A protein

Clonality

Polyclonal

Host

Sheep

Isotype

IgG

Theoretical MW

102.4 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Description

Novus Biologicals Sheep Epstein Barr Virus Nuclear Antigen 3A Antibody (NBP2-66589) is a polyclonal antibody validated for use in WB. All Novus Biologicals antibodies are covered by our 100% guarantee.

Scientific Data Images for Epstein Barr Virus Nuclear Antigen 3A Antibody

Western Blot: Epstein Barr Virus Nuclear Antigen 3A Antibody [NBP2-66589]

Western Blot: Epstein Barr Virus Nuclear Antigen 3A Antibody [NBP2-66589]

Western Blot: Epstein Barr Virus Nuclear Antigen 3A Antibody [NBP2-66589] - Analysis using EBNA-3A antibody on cell lines infected with Epstein Barr virus.

Applications for Epstein Barr Virus Nuclear Antigen 3A Antibody

Application
Recommended Usage

Western Blot

0.25-1 ug/ml
Application Notes
.

Formulation, Preparation, and Storage

Purification

Whole Antiserum

Formulation

Delipidated, heat inactivated, lyophilized stable whole serum

Preservative

No Preservative

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Epstein Barr Virus Nuclear Antigen 3A

EBNA-3A is a latent viral nuclear protein expressed in EBV transformed lymphoblastic cell lines. It is also found in some immunoblastic lymphomas in vivo. This viral nuclear protein is essential for EBV mediated transformation of B lymphocytes. The EBNA-3A functions as a transcriptional regulator though the target genes are currently unknown. Plays an essential role for activation and immortalization of human B-cells. Represses transcription of viral promoters TP1 and Cp through interaction with host RBPJ, and inhibits EBNA2-mediated activation of these promoters. Since Cp is the promoter for all EBNA mRNAs, EBNA3A probably contributes to a negative autoregulatory control loop.

Additional Epstein Barr Virus Nuclear Antigen 3A Products

Product Documents for Epstein Barr Virus Nuclear Antigen 3A Antibody

Product Datasheets

Certificate of Analysis

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Product Specific Notices for Epstein Barr Virus Nuclear Antigen 3A Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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