EMMPRIN/CD147 Antibody (24GB5555)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-51724

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NBP3-51724-100ul
NBP3-51724-20ul
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Key Product Details

Species Reactivity

Human

Applications

Western Blot, Flow Cytometry, Knockdown Validated

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2B Clone # 24GB5555

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all EMMPRIN/CD147 Antibodies »

Product Specifications

Immunogen

Recombinant protein of human EMMPRIN/CD147 (Uniprot: P35613)

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2B

Scientific Data Images for EMMPRIN/CD147 Antibody (24GB5555)

EMMPRIN/CD147 Antibody (24GB5555)

Flow Cytometry: EMMPRIN/CD147 Antibody (24GB5555)[NBP3-51724] -

Flow cytometric analysis of EMMPRIN/CD147expression in HeLa cells using EMMPRIN/CD147 antibody (1:2,000). Green, isotype control; red, BSG.

Applications for EMMPRIN/CD147 Antibody (24GB5555)

Application
Recommended Usage

Flow Cytometry

Optimal dilutions of this antibody should be experimentally determined.

Knockdown Validated

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.4), 50% glycerol

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: EMMPRIN/CD147

CD147 plays a pivotal role in spermatogenesis, embryo implantation, neural network formation and tumor progression. It stimulates adjacent fibroblasts to produce matrix metalloproteinases (MMPS). CD147 may target monocarboxylate transporters SLC16A1, SLC16A3 and SLC16A8 to plasma membranes of retinal pigment epithelium and neural retina. CD147 also seems to be a receptor for oligomannosidic glycans. In vitro, it promotes outgrowth of astrocytic processes. CD147 forms homooligomers in a cis-dependent manner on the plasma membrane. It forms a complex with MMP1 at the tumor cell surface. CD147 interacts with SLC16A1 and SLC1A3; probably a BSG dimer is associated with a monocarboxylate transporter dimer. CD147 also interacts with ATP1B2, MAG and L1CAM.

Long Name

Extracellular Matrix Metalloproteinase Inducer

Alternate Names

Basigin, BSG, CD147

Gene Symbol

BSG

Additional EMMPRIN/CD147 Products

Product Documents for EMMPRIN/CD147 Antibody (24GB5555)

Product Datasheets

Certificate of Analysis

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Product Specific Notices for EMMPRIN/CD147 Antibody (24GB5555)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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