DYNC1H1 Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-46613

Novus Biologicals, part of Bio-Techne
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NBP3-46613
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Key Product Details

Species Reactivity

Human, Mouse, Rat, Zebrafish

Applications

Immunohistochemistry, Western Blot, ELISA, Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all DYNC1H1 Antibodies »

Product Specifications

Immunogen

dynein, cytoplasmic 1, heavy chain 1. (Uniprot# Q14204)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

532 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Description

Novus Biologicals Rabbit DYNC1H1 Antibody - BSA Free (NBP3-46613) is a polyclonal antibody validated for use in IHC, WB, ELISA and ICC/IF. All Novus Biologicals antibodies are covered by our 100% guarantee.

Scientific Data Images for DYNC1H1 Antibody - BSA Free

DYNC1H1 Antibody - BSA Free

Western Blot: DYNC1H1 Antibody - BSA Free [NBP3-46613] -

Western Blot: DYNC1H1 Antibody - BSA Free [NBP3-46613] - HeLa cells were subjected to SDS PAGE followed by western blot with (DYNC1H1 antibody) at dilution of 1:500
DYNC1H1 Antibody - BSA Free

Immunohistochemistry: DYNC1H1 Antibody - BSA Free [NBP3-46613] -

Immunohistochemistry: DYNC1H1 Antibody - BSA Free [NBP3-46613] - Immunohistochemistry of paraffin-embedded human breast cancer using (DYNC1H1 antibody) at dilution of 1:100

Applications for DYNC1H1 Antibody - BSA Free

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:20-1:200

Immunohistochemistry

1:20-1:200

Western Blot

1:500-1:2000

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS, 50% Glycerol, pH (7.3)

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: DYNC1H1

The DYNC1H1 gene encodes a cytoplasmic dynein 1 heavy chain 1 protein that is 4,646 amino acids long at 532 kDA. Dyneines function as molecular motors that contain ATPase activity. Defects in DYNC1H1 cause Charcot-Marie-Tooth Disease type 2O (CMT2O), mental retardation autosomal dominant type 13 (MRD13), as well as spinal muscular atrophy, lower extremity, autosomal dominant (SMALED). DYNC1H1 has also been investigated by researchers in myeloma, neuropathy, ciliary dyskinesia, lateral sclerosis, intellectual disabilities, lissencephaly, schizophrenia, malaria, and neurodegeneration. DYNC1H1 participates in centrosome maturation, adaptive immune system, cytoplasmic microtubules, cell cycle spindle assembly and chromosome separation, as well as phagosome and vasopressin-regulated water reabsorption. DYNC1H1 interacts with genes HIST1H4A, HIST1H4B, HIST1H4C, HIST1H4D, and HIST1H43.

Alternate Names

cytoplasmic dynein 1 heavy chain 1, Cytoplasmic dynein heavy chain 1, DHC1a, DHC1Dynein heavy chain, cytosolic, DKFZp686P2245, Dnchc1, DNCLDNCH1, DNECLDYHC, dynein, cytoplasmic 1, heavy chain 1, dynein, cytoplasmic, heavy polypeptide 1, HL-3, KIAA0325, p22

Gene Symbol

DYNC1H1

Additional DYNC1H1 Products

Product Documents for DYNC1H1 Antibody - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for DYNC1H1 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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