Cysteinyl Leukotriene R1/CysLTR1 Antibody - BSA Free
Novus Biologicals, part of Bio-Techne | Catalog # NBP1-85356
![Immunohistochemistry-Paraffin: Cysteinyl Leukotriene R1/CysLTR1 Antibody [NBP1-85356]](https://resources.bio-techne.com/images/products/Cysteinyl-Leukotriene-R1-CysLTR1-Antibody-Immunohistochemistry-Paraffin-NBP1-85356-img0007.jpg "Immunohistochemistry-Paraffin: Cysteinyl Leukotriene R1/CysLTR1 Antibody [NBP1-85356]")
Key Product Details
Species Reactivity
Validated:
Human
Predicted:
Mouse (92%). Backed by our 100% Guarantee.
Applications
Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot
Label
Unconjugated
Antibody Source
Polyclonal Rabbit IgG
Format
BSA Free
Concentration
Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.
Product Specifications
Immunogen
This antibody was developed against Recombinant Protein corresponding to amino acids: RLSTFRKHSLSSVTYVPRKKASLPE
Reactivity Notes
Immunogen displays the following percentage of sequence identity for non-tested species: Rat (88%)
Clonality
Polyclonal
Host
Rabbit
Isotype
IgG
Description
Novus Biologicals Rabbit Cysteinyl Leukotriene R1/CysLTR1 Antibody - BSA Free (NBP1-85356) is a polyclonal antibody validated for use in IHC and WB. All Novus Biologicals antibodies are covered by our 100% guarantee.
Scientific Data Images for Cysteinyl Leukotriene R1/CysLTR1 Antibody - BSA Free
![Western Blot: Cysteinyl Leukotriene R1/CysLTR1 Antibody [NBP1-85356]](https://resources.bio-techne.com/images/products/Cysteinyl-Leukotriene-R1-CysLTR1-Antibody-Western-Blot-NBP1-85356-img0005.jpg "Western Blot: Cysteinyl Leukotriene R1/CysLTR1 Antibody [NBP1-85356]")
Western Blot: Cysteinyl Leukotriene R1/CysLTR1 Antibody [NBP1-85356]
Western Blot: Cysteinyl Leukotriene R1/CysLTR1 Antibody [NBP1-85356] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11. Lane 2: Human cell line RT-4. Lane 3: Human cell line U-251MG sp![Immunohistochemistry-Paraffin: Cysteinyl Leukotriene R1/CysLTR1 Antibody [NBP1-85356]](https://resources.bio-techne.com/images/products/Cysteinyl-Leukotriene-R1-CysLTR1-Antibody-Immunohistochemistry-Paraffin-NBP1-85356-img0010.jpg "Immunohistochemistry-Paraffin: Cysteinyl Leukotriene R1/CysLTR1 Antibody [NBP1-85356]")
Immunohistochemistry-Paraffin: Cysteinyl Leukotriene R1/CysLTR1 Antibody [NBP1-85356]
Immunohistochemistry-Paraffin: Cysteinyl Leukotriene R1/CysLTR1 Antibody [NBP1-85356] - Staining of human spleen shows strong cytoplasmic/membranous positivity in cells in red pulp.![Immunohistochemistry-Paraffin: Cysteinyl Leukotriene R1/CysLTR1 Antibody [NBP1-85356]](https://resources.bio-techne.com/images/products/Cysteinyl-Leukotriene-R1-CysLTR1-Antibody-Immunohistochemistry-Paraffin-NBP1-85356-img0006.jpg "Immunohistochemistry-Paraffin: Cysteinyl Leukotriene R1/CysLTR1 Antibody [NBP1-85356]")
Immunohistochemistry-Paraffin: Cysteinyl Leukotriene R1/CysLTR1 Antibody [NBP1-85356]
Immunohistochemistry-Paraffin: Cysteinyl Leukotriene R1/CysLTR1 Antibody [NBP1-85356] - Staining of human lung shows strong cytoplasmic positivity in macrophages.![Immunohistochemistry-Paraffin: Cysteinyl Leukotriene R1/CysLTR1 Antibody [NBP1-85356]](https://resources.bio-techne.com/images/products/Cysteinyl-Leukotriene-R1-CysLTR1-Antibody-Immunohistochemistry-Paraffin-NBP1-85356-img0008.jpg "Immunohistochemistry-Paraffin: Cysteinyl Leukotriene R1/CysLTR1 Antibody [NBP1-85356]")
![Immunohistochemistry-Paraffin: Cysteinyl Leukotriene R1/CysLTR1 Antibody [NBP1-85356]](https://resources.bio-techne.com/images/products/Cysteinyl-Leukotriene-R1-CysLTR1-Antibody-Immunohistochemistry-Paraffin-NBP1-85356-img0009.jpg "Immunohistochemistry-Paraffin: Cysteinyl Leukotriene R1/CysLTR1 Antibody [NBP1-85356]")
Applications for Cysteinyl Leukotriene R1/CysLTR1 Antibody - BSA Free
Application
Recommended Usage
Immunohistochemistry
1:200 - 1:500
Immunohistochemistry-Paraffin
1:200 - 1:500
Western Blot
0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Formulation, Preparation, and Storage
Purification
Affinity purified
Formulation
PBS (pH 7.2) and 40% Glycerol
Format
BSA Free
Preservative
0.02% Sodium Azide
Concentration
Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Background: Cysteinyl Leukotriene R1/CysLTR1
The cysteinyl leukotrienes LTC4, LTD4, and LTE4 are important mediators of human bronchial asthma. Pharmacologic studies have determined that cysteinyl leukotrienes activate at least 2 receptors, CysLTR1 and CysLTR2. Both receptors are members of the superfamily of G protein-coupled receptors. Activation of CysLTR1 by LTD4 results in contraction and proliferation of smooth muscle, oedema, eosinophil migration and damage to the mucus layer in the lung.
Long Name
Cysteinyl Leukotriene Receptor 1
Alternate Names
CysLT1, CysLTR1, Cysteinyl LeukotrieneR1, HG55, HMTMF81, LTD4 Receptor
Gene Symbol
CYSLTR1
Additional Cysteinyl Leukotriene R1/CysLTR1 Products
Product Documents for Cysteinyl Leukotriene R1/CysLTR1 Antibody - BSA Free
Product Specific Notices for Cysteinyl Leukotriene R1/CysLTR1 Antibody - BSA Free
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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