CSE1L/CAS/Exportin-2 Antibody (1W4T4)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-15330

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-15330-100ul
NBP3-15330-20ul
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Key Product Details

Species Reactivity

Human, Mouse

Applications

Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # 1W4T4 expressed in HEK293

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all CSE1L/CAS Antibodies »

Product Specifications

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 872-971 of human CSE1L/CAS/Exportin-2 (P55060). LIGLFELPEDDTIPDEEHFIDIEDTPGYQTAFSQLAFAGKKEHDPVGQMVNNPKIHLAQSLHKLSTACPGRVPSMVSTSLNAEALQYLQGYLQAASVTLL

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Description

Novus Biologicals Rabbit CSE1L/CAS/Exportin-2 Antibody (1W4T4) (NBP3-15330) is a recombinant monoclonal antibody validated for use in WB. All Novus Biologicals antibodies are covered by our 100% guarantee.

Scientific Data Images for CSE1L/CAS/Exportin-2 Antibody (1W4T4)

Western Blot: CSE1L/CAS/Exportin-2 Antibody (1W4T4) [NBP3-15330]

Western Blot: CSE1L/CAS/Exportin-2 Antibody (1W4T4) [NBP3-15330]

Western Blot: CSE1L/CAS/Exportin-2 Antibody (1W4T4) [NBP3-15330] - Western blot analysis of extracts of various cell lines, using CSE1L/CAS/Exportin-2 Rabbit mAb (NBP3-15330) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 10s.

Applications for CSE1L/CAS/Exportin-2 Antibody (1W4T4)

Application
Recommended Usage

Western Blot

1:500 - 1:1000

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.3), 50% glycerol, 0.05% BSA

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: CSE1L/CAS

Proteins that carry a nuclear localization signal (NLS) are transported into the nucleus by the importin-alpha/beta heterodimer. Importin-alpha binds the NLS, while importin-beta mediates translocation through the nuclear pore complex. After translocation, RanGTP binds importin-beta and displaces importin-alpha. Importin-alpha must then be returned to the cytoplasm, leaving the NLS protein behind. The protein encoded by this gene binds strongly to NLS-free importin-alpha, and this binding is released in the cytoplasm by the combined action of RANBP1 and RANGAP1. In addition, the encoded protein may play a role both in apoptosis and in cell proliferation.

Long Name

Chromosome segregation 1-like protein

Alternate Names

CAS, CSE1, XPO2

Gene Symbol

CSE1L

Additional CSE1L/CAS Products

Product Documents for CSE1L/CAS/Exportin-2 Antibody (1W4T4)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for CSE1L/CAS/Exportin-2 Antibody (1W4T4)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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