Connexin 26/GJB2 Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-41304

Novus Biologicals, part of Bio-Techne

Key Product Details

Validated by

Biological Validation

Species Reactivity

Validated:

Human, Rat, Porcine

Cited:

Rat

Predicted:

Mouse (94%). Backed by our 100% Guarantee.

Applications

Validated:

ELISA, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Cited:

Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1 mg/ml

View all Connexin 26/GJB2 Antibodies »

Product Specifications

Immunogen

Antibody was raised against a 16 amino acid peptide near the center of human GJB2. The immunogen is located within amino acids 80 - 130 of GJB2. Amino Acid Squence: HVAYRRHEKKRKFIKGE

Reactivity Notes

Predicted species reactivity based on immunogen sequence: Sheep: (88%), Bovine: (88%), Chicken: (82%)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

26 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for Connexin 26/GJB2 Antibody - BSA Free

Western Blot: Connexin 26/GJB2 AntibodyBSA Free [NBP2-41304]

Western Blot: Connexin 26/GJB2 AntibodyBSA Free [NBP2-41304]

Connexin-26-GJB2-Antibody-Western-Blot-NBP2-41304-img0005.jpg
Immunocytochemistry/ Immunofluorescence: Connexin 26/GJB2 Antibody - BSA Free [NBP2-41304]

Immunocytochemistry/ Immunofluorescence: Connexin 26/GJB2 Antibody - BSA Free [NBP2-41304]

Connexin-26-GJB2-Antibody-Immunocytochemistry-Immunofluorescence-NBP2-41304-img0002.jpg
Immunohistochemistry: Connexin 26/GJB2 Antibody - BSA Free [NBP2-41304]

Immunohistochemistry: Connexin 26/GJB2 Antibody - BSA Free [NBP2-41304]

Connexin-26-GJB2-Antibody-Immunohistochemistry-NBP2-41304-img0004.jpg
View 2 more images

Applications for Connexin 26/GJB2 Antibody - BSA Free

Application
Recommended Usage

Western Blot

1 - 2 ug/ml
Application Notes
Use in IHC-P reported in scientific literature (PMID:33171391)

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Connexin 26/GJB2

Connexin-26 / GJB2 is a gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexins, through which materials of low molecular weight diffuse from one cell to a neighboring cell. Each connexin is composed of a hexamer of connexin proteins. Connexins are a multi-gene family of highly related proteins. At least a dozen distinct connexin genes have been identified and many are expressed in a tissue-specific manner. Two distinct lineages, class I (beta) and class II (alpha), have been identified in mammals. Connexin-26 belongs to the class 1 (beta) group of connexins. Mutations in Connexin-26 are associated with genetically derived hearing impairments, including autosomal recessive non syndromic deafness.

Alternate Names

CX26, DFNA3, DFNB1, GJB2, HID, KID, NSRD1, PPK

Gene Symbol

GJB2

Additional Connexin 26/GJB2 Products

Product Documents for Connexin 26/GJB2 Antibody - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for Connexin 26/GJB2 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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