CCR3 Antibody (5E8) - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-09149

Novus Biologicals, part of Bio-Techne
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NBP3-09149
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Key Product Details

Species Reactivity

Human

Applications

Flow Cytometry

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2b Kappa Clone # 5E8

Format

BSA Free

Concentration

1 mg/ml

View all CCR3 Antibodies »

Product Specifications

Immunogen

Tissue / cell preparation (Human) - human CCR3 transfected into mouse B cell lymphoma L1.2 cells.

Specificity

The mouse monoclonal antibody 5E8 recognizes an extracellular epitope of CD193 (chemokine receptor 3), an approximately 41 kDa protein expressed above all in eosinophils and basophils.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2b Kappa

Description

Novus Biologicals Mouse CCR3 Antibody (5E8) - BSA Free (NBP3-09149) is a monoclonal antibody validated for use in Flow. All Novus Biologicals antibodies are covered by our 100% guarantee.

Scientific Data Images for CCR3 Antibody (5E8) - BSA Free

Flow Cytometry: CCR3 Antibody (5E8) - BSA Free [NBP3-09149]

Flow Cytometry: CCR3 Antibody (5E8) - BSA Free [NBP3-09149]

Flow Cytometry: CCR3 Antibody (5E8) [NBP3-09149] - Analysis (surface staining) of CD193 in human peripheral blood with anti-human CD193 (5E8) purified, GAM-APC.

Applications for CCR3 Antibody (5E8) - BSA Free

Application
Recommended Usage

Flow Cytometry

1-4 ug/ml

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

Phosphate buffered saline (PBS), pH 7.4

Format

BSA Free

Preservative

15mM Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: CCR3

CKR3, or C-C chemokine receptor type 3, is a G protein-coupled, seven-transmembrane domain receptor protein. The chemokine eotaxin appears to be a highly specific agonist for CKR3, making CKR3 one of the factors responsible for selective recruitment of eosinophils to sites of inflammation (1). It has been shown that more than one chemokine activates CKR3, including eotaxin, RANTES, and MCP-3 (2). Since CKR3 is prominently expressed in eosinophils , it has been named the human eosinophil eotaxin receptor (2,3).

Alternate Names

CCR3, CD193

Gene Symbol

CCR3

Additional CCR3 Products

Product Documents for CCR3 Antibody (5E8) - BSA Free

Product Datasheets

Certificate of Analysis

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Product Specific Notices for CCR3 Antibody (5E8) - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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