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Caveolin-3 Antibody (23GB3035)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-51068

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NBP3-51068-100ul
NBP3-51068-20ul

Key Product Details

Species Reactivity

Human, Rat

Applications

Western Blot, Flow Cytometry, Immunocytochemistry/ Immunofluorescence, Knockdown Validated

Label

Unconjugated

Antibody Source

Monoclonal Rabbit IgG Clone # 23GB3035

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

A synthesized peptide derived from Caveolin-3 (Uniprot: P56539)

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Caveolin-3 Antibody (23GB3035)

Caveolin-3 Antibody (23GB3035)

Immunocytochemistry/ Immunofluorescence: Caveolin-3 Antibody (23GB3035)[NBP3-51068] -

Immunocytochemical staining of HT-1080 cells with Caveolin-3 antibody (1:1,000). Nuclei were stained blue with DAPI; Caveolin-3 was stained magenta with Alexa Fluor(R) 647. Images were taken using Leica stellaris 5. Protein abundance based on laser Intensity and smart gain: Medium. Scale bar, 20 um.
Caveolin-3 Antibody (23GB3035)

Flow Cytometry: Caveolin-3 Antibody (23GB3035)[NBP3-51068] -

Flow cytometric analysis of Caveolin-3expression in C2C12 cells using Caveolin-3 antibody (1:2,000). Green, isotype control; red, Caveolin 3.
Caveolin-3 Antibody (23GB3035)

Western Blot: Caveolin-3 Antibody (23GB3035)[NBP3-51068] -

Western blotting analysis using Caveolin-3 antibody (1:5,000) and HRP-conjugated goat anti-rabbit secondary antibody (1:20,000) respectively. Image was developed using FeQ(TM) ECL Substrate Kit.

Applications for Caveolin-3 Antibody (23GB3035)

Application
Recommended Usage

Flow Cytometry

Optimal dilutions of this antibody should be experimentally determined.

Immunocytochemistry/ Immunofluorescence

Optimal dilutions of this antibody should be experimentally determined.

Knockdown Validated

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.4), 50% glycerol

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: Caveolin-3

Caveolin 3 encodes a caveolin family member, which functions as a component of the caveolae plasma membranes found in most cell types. Caveolin proteins are proposed to be scaffolding proteins for organizing and concentrating certain caveolin-interacting molecules. Mutations identified in this gene lead to interference with protein oligomerization or intra-cellular routing, disrupting caveolae formation and resulting in Limb-Girdle muscular dystrophy type-1C (LGMD-1C), hyperCKemia or rippling muscle disease (RMD). Alternative splicing has been identified for this locus, with inclusion or exclusion of a differentially spliced intron. In addition, transcripts utilize multiple polyA sites and contain two potential translation initiation sites.

Alternate Names

CAV3, Caveolin3, LGMD1C, LQT9, M-caveolin

Gene Symbol

CAV3

Additional Caveolin-3 Products

Product Documents for Caveolin-3 Antibody (23GB3035)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Caveolin-3 Antibody (23GB3035)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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