c-jun Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NB600-1482

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NB600-1482
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Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Immunohistochemistry, Western Blot, Immunoprecipitation

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

0.2 mg/ml

View all c-Jun Antibodies »

Product Specifications

Immunogen

Synthetic peptide (Mouse) (N terminal).

Localization

Nuclear

Specificity

Reacts with c-Jun p39

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for c-jun Antibody

Western Blot: c-jun Antibody [NB600-1482]

Western Blot: c-jun Antibody [NB600-1482]

Western Blot: c-jun Antibody [NB600-1482] - Analysis of c-Jun p39 expression in Jurkat whole cell lysates.

Applications for c-jun Antibody

Application
Recommended Usage

Immunohistochemistry

1:10-1:500

Immunoprecipitation

1:10-1:500

Western Blot

1:400

Formulation, Preparation, and Storage

Purification

IgG purified

Formulation

PBS, 100 ug BSA.

Preservative

0.1% Sodium Azide

Concentration

0.2 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: c-Jun

The human protooncogene JUN is the putative transforming gene of avian sarcoma virus 17, and it encodes a protein which is highly homologous to the viral protein. cJun (previously known as the Fos binding protein p39) and c Fos form a complex in the nucleus. AP 1 (activating protein 1) is a collective term referring to these dimeric transcription factors composed of Jun, Fos or ATF subunits that bind to a common DNA site, the AP1 binding site. AP 1 proteins, mostly the Jun group, regulate the expression and function of cell cycle regulators such as Cyclin D1, p53, p21 (cip1/waf1), p19 (ARF) and p16. Fos and Jun proto oncogene expression is induced transiently by a variety of extracellular stimuli associated with mitogenesis, differentiation processes or depolarization of neurons. JUN has been mapped to 1p32 to p31, a chromosomal region involved in both translocations and deletions in human malignancies.

Long Name

Cellular Repressor of E1A-stimulated Genes/Transcription Factor AP-1

Alternate Names

cJun, JUN

Entrez Gene IDs

3725 (Human); 16476 (Mouse); 24516 (Rat)

Gene Symbol

JUN

Additional c-Jun Products

Product Documents for c-jun Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for c-jun Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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